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Cancer therapeutics : experimental and clinical agents /

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This comprehensive review of existing and potential anticancer drugs and therapies by leading researchers from academia, government laboratories, and pharmaceutical companies offers essential insight into what has been accomplished and where the experimental therapy of cancer is going. The authorita...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Teicher, Beverly A., 1952-
Format: eBook
Language:English
Published: Totowa, N.J. : Humana, [1997]
Series:Cancer drug discovery and development.
Subjects:
Antineoplastic agents.
Antineoplastic Agents.
Cytostatikum.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • pt. 1. Cytotoxic agents: old and new
  • Nitrogen mustards
  • Phosphoramide and oxazaphosphorine mustards
  • Development of the nitrosoureas
  • Platinum complexes
  • Anthracyclines
  • Topoisomerase I inhibitors
  • DNA topoisomerase II inhibitors
  • The toxoids
  • Sequence-selective groove binders
  • Bis-naphthalimides: synthesis and preclinical evaluation
  • pt. 2. Newer strategies and targets
  • The enediynes
  • Matrix metalloproteinase inhibitors
  • Interferons and other cytokines
  • Discovery of TNP-470 and other angiogenesis inhibitors
  • Antisense oligonucleotides
  • Growth factores and growth factor inhibitors
  • Immunoconjugates
  • A case for ras targeted agents as antineoplastics
  • Gene therapy.