Nucleic acid therapeutics in cancer /

The development of effectively targeted and efficiently delivered nucleic acids promises important advances in the diagnosis and treatment of human malignancies. In Nucleic Acid Therapeutics in Cancer, leading researchers, academic physicians, and clinicians clearly and succinctly review the importa...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Gewirtz, A. M. (Alan M.)
Format: eBook
Language:English
Published: Totowa, N.J. : Humana Press, [2004]
Series:Cancer drug discovery and development.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:The development of effectively targeted and efficiently delivered nucleic acids promises important advances in the diagnosis and treatment of human malignancies. In Nucleic Acid Therapeutics in Cancer, leading researchers, academic physicians, and clinicians clearly and succinctly review the important issues underlying the therapeutic use of nucleic acid-mediated gene silencing. Topics range from basic methodology and delivery to targeting methods and specific clinical targets. The authors thoroughly explain the latest developments in RNA biology, as well as the underpinnings of RNA interference, oligodeoxynucleotide delivery into cells, and strategies for targeting these molecules to accessible regions within the mRNA. They also provide some examples of how these new therapeutic compounds are being used clinically. Concise yet highly readable, Nucleic Acid Therapeutics in Cancer offers those who require a cutting-edge critical synthesis not only a state-of-the-art account of this promising field, but also an illuminating introduction to their emerging therapeutic uses.
Item Description:Papers from a conference held Apr. 2000 in Bryn Mawr, Pa.
Electronic resource.
Physical Description:1 online resource (219 pages) : illustrations (some color).
Format:Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Bibliography:Includes bibliographical references and index.
ISBN:1592597777 (electronic bk.)
9781592597772 (electronic bk.)