http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
1 online resource (xiii, 509 pages) : illustrations (some color)
After decades of intense experimental work by a number of different investigators, it is now clearly recognized that the ability of stem cells to give rise to broad variety of differentiated cell types is critical not only to the emergence of new and more effective treatments for human diseases, but also to understanding the pathogenesis of congenital abnormalities and cancer. In Stem Cells Handbook, leading scientists in the field survey the "state-of-the-science" of stem cell biology, explaining the origin of stem cells, and describing how they function, how they can cause illness, and how they might be employed to cure or ameliorate disease. In particular, the authors discuss the roles of stem cells in development and organogenesis, in normal tissue turnover, in the repair response to injury, and in carcinogenesis. They also explain how to obtain stem cells from different organs, culture them in vitro, and manipulate them for therapeutic use. The book highlights the promise of using embryonic and adult tissue stem cells in both animal models and human diseases for the replacement of damaged tissue, for the treatment of cancer, for cell replacement, and for gene therapy treatments of genetic and metabolic diseases. Comprehensive and authoritative, Stem Cells Handbook not only critically reviews and summarizes the diverse studies now being carried out on this highly promising class of cells, but also constitutes every investigator's gold-standard reference on stem cell biology and medicine today.
Stem cells : what are they? where do they come from? why are they here? when do they go wrong? where are they going? / Stewart Sell -- Stem cells from early mammalian embryos: common themes and significant differences / Virginia E. Papaioannou and Anna-Katerina Hadjantonakis -- Embryonic stem cells: isolation and application of pluripotent cells from the pregastrulation mammalian embryo / Joy Rathjen and Peter David Rathjen -- From stem cells to functional tissue architecture: what are the signals and how are they processed? / Sui Huang and Donald E. Ingber -- Germline stem cells / Haifan Lin -- Stem cells and cloning / Ian Wilmut and Lesley Ann Paterson -- Genomic imprinting in mouse embryonic stem and germ cells / Jeffrey R. Mann and Piroska E. Szabo Stem cells in amphibian regeneration / David L. Stocum -- Stem cells in dermal wound healing / William J. Lindblad -- Bone marrow mesenchymal stem cells / James E. Dennis and Arnold L. Caplan -- Normal and leukemic hematopoietic stem cells and lineages / Ernest A. McCulloch Developmental origin of murine hematopoietic stem cells / Lorraine Robb and Kyunghee Choi -- stromal support of hematopoiesis / Pierre Charbord -- Hematopoietic stem cells: identification, characterization, and assays / Ian Ponting, Yi Zhao and W. French Anderson -- Hematopoietic stem cells in leukemia and lymphoma / Stephen M. Baird -- Neurons, stem cells, and potential therapies / Fiona C. Mansergh, Michael A. Wride, and Derrick E. Rancourt -- Neural stem cells: from in vivo to in vitro and back again-practical aspects / Michael A. Marconi [and others] -- Molecular genetic approaches in the study of retinal progenitor cells and stem cells / Till Marquardt and Peter Gruss -- Endothelial progenitor cells / Takayuki Asahara and Jeffrey M. Isner -- Development of the cardiovascular system in embryoid bodies derived from embryonic stem cells / Heinrich Sauer [and others] -- Transcription factors, growth factors, and signal cascades capable of priming cardiogenesis / Agapios Sachinidis [and others] -- Strategies using cell therapy to induce cardiomyocyte regeneration in adults with heart disease / Silviu Itescu -- Generation and stem cell repair of cardiac tissues / Kathyjo A. Jackson and Margaret A. Goodell -- Stem cells in kidney morphogenesis / Emma M.A. Ball and Gail P. Risbridger -- nephroblastoma : a metanephric caricature / Alan 0. Perantoni -- Stem cells in nonmelanoma skin cancer / Wendy C. Weinberg and Stuart H. Yuspa -- The stem cell plasticity of aggressive melanoma tumor cells / Mary J.C. Hendrix [and others] -- Stem cells in glandular organs / Karin Williams and Simon W. Hayward -- Gastrointestinal stem cells: proliferation kinetics and differentiation hierarchies / Sherif M. Karam -- Stem cell origin of cell lineages, proliferative units, and cancer in the gastrointestinal tract / Mairi Brittan and Nicholas A. Wright -- specification of liver from embryonic endoderm / Hideyuki Yoshitomi and Kenneth S. Zaret -- Animal models for assessing the contribution of stem cells to liver development / Douglas C. Hixson -- Normal liver progenitor cells in culture / Katherine S. Koch and Hyam L. Leffert -- Permanent lines of stem cells from the liver / Helene Strick-Marchand and Mary C. Weiss -- Biology of human liver stem cells / Alastair J. Strain, Sarbjit S. Nijjar, and Heather A. Crosby -- Transplantation of hepatic stem cells and potential applications for cell therapy / Sanjeev Gupta and Jae-Jin Cho -- Plasticity of adult-derived pancreatic stem cells / Ammon B. Peck and Vijayakumar K. Ramiya -- Islet cells / Luc Bouwens -- Mammary epithelial stem cells / Gilbert H. Smith / Morphogenesis of prostate cancer / Helmut Bonkhoff -- Stem cells in lung morphogenesis, regeneration, and carcinogenesis / Ank A.W. ten Have-Opbroek, Scott H. Randell, and Barry R. Stripp -- Noninvasive imaging in stem cell therapies : current state and future perspectives / Juri Gelovani -- what is the future for stem cell research? : whether entity or function? / Regis Doyonnas and Helen M. Blau.
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL
Includes bibliographical references and index.