Cover Image

Quinolone antibacterials /

Show other versions (1)

The quinolones continue to make a significant contribution in the fight against community or hospital acquired infections and add a new dimension of antibacterial therapy. This volume describes in detail the chemistry, mode of action and pharmacodynamics of the quinolones. A lot of effort has been u...

Full description

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Beermann, D., Kuhlmann, J. (Jochen), Dalhoff, Axel, Zeiler, H. J. (Hans-Joachim), 1947-
Format: eBook
Language:English
Published: Berlin ; New York : Springer, [1998]
Series:Handbook of experimental pharmacology ; v. 127.
Subjects:
Quinolone antibacterial agents.
Quinolones > pharmacology.
Anti-Infective Agents > therapeutic use.
Quinolones > therapeutic use.
Chinolonen.
Antibacteriële middelen.
Gyrasehemmer.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • History and Introduction
  • The Chemistry of the Quinolones: Methods of Synthesizing the Quinolone Ring System
  • Chemistry in the Periphery of the Quinolones
  • Mode of Action
  • The In Vitro Antibacterial Activity of Quinolones: A Review
  • Pharmacokinetics of Fluoroquinolones in Experimental Animals
  • Pharmacodynamics of Fluoroquinolones in Experimental Animals
  • Interaction of Quinolones with Host-Parasite-Relationships
  • Mechanisms of Resistance to Fluoroquinolones
  • Toxicology and Safety Pharmacology of Quinolones
  • Clinical Pharmacology
  • Concentration-Effect Relationship of the Fluoroquinolones
  • Clinical Use of Quinolones
  • Future Aspects.