Intracellular signal transduction : the JAK-STAT pathway /
This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilisi...
| Main Author: | |
|---|---|
| Corporate Author: | |
| Other Authors: | |
| Format: | eBook |
| Language: | English |
| Published: |
New York : Austin :
Springer ; R.G. Landes,
[1996]
|
| Series: | Molecular biology intelligence unit (Unnumbered)
|
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself. An interesting addition to the book is the chapter on the use of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling. |
|---|---|
| Item Description: | Electronic resource. |
| Physical Description: | 1 online resource (209 pages) : illustrations. |
| Bibliography: | Includes bibliographical references (pages 169-202) and index. |
| ISBN: | 9783662220504 (electronic bk.) 3662220504 (electronic bk.) |