Impedimetric biosensors for medical applications : current progress and challenges /
| Main Authors: | , , , , , |
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| Corporate Author: | |
| Format: | eBook |
| Language: | English |
| Published: |
New York, [New York] : New York, [New York] (222 East 46th Street, New York, NY 10017) :
ASME ; Momentum Press,
2013.
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| Series: | Biomedical & nanomedical technologies.
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Abstract: | In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer- by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalisation and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph describes case studies of successful impedance-based biosensors for the detection of a range of analytes from small molecules up to whole microorganisms. Finally, the authors put forward future perspectives for the clinical applications of impedimetric biosensors. |
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| Item Description: | Electronic resource. |
| Physical Description: | 1 online resource (70 pages) : illustrations. Also available in print. |
| Format: | Mode of access: World Wide Web. System requirements: Adobe Acrobat reader. |
| Bibliography: | Includes bibliographical references (pages 57-70). |
| ISBN: | 9781606506370 |
| Access: | Restricted to libraries which purchase an unrestricted PDF download via an IP. |