rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    non sort: The
    title: Effect of Thymol-B-D-Glucopyranoside on the Reduction of Campylobacter Species in Food-Producing Animals
  name:
    name part: Epps, Sharon V.R.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Phillips, Timothy D.
    role:
      role term: thesis advisor.
  name:
    name part: Harvey, Roger Bruce
    name part: 1946-
    role:
      role term: thesis advisor.
  name:
    name part: Texas A & M University
    role:
      role term: degree granting institution.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: txu
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource.
  abstract: Campylobacter are a leading cause of bacterial derived foodborne illness. Thymol is a natural product that reduces survivability of Campylobacter in vitro. Results from animal studies, however, indicate that absorption or degradation within the stomach and small intestine may preclude delivery of thymol to the cecum and large intestine, the main sites of Campylobacter colonization. Presently, we compared the anti- Campylobacter activity of thymol against that of thymol-β-D-glucopyranoside (β-Dthymol), the latter suspected to be resistant to degradation and absorption in the proximal alimentary tract lacking β-glycosidase activity. When treated with 1 mM thymol, the survivability of Campylobacter coli and jejuni in vitro was reduced by 3.41 to 6.87 log_10 CFU mL-1 after 48-h pure culture and after co-culture, respectively. In the presence of a β-glycosidase-expressing Parabacteroides distasonis. Conversely, the survivability of C. coli and C. jejuni was reduced by 3.72 and 4.30 log_10 CFU mL-1, respectively, in cocultures treated with β-D-thymol, but not in pure cultures similarly treated. When tested in mixed cultures of porcine or bovine fecal microbes possessing endogenous β- glycosidase, C. coli and C. jejuni survivability was reduced by 3.26 and 2.50 log_10 CFU mL-1, respectively, whether treated with thymol or β-D-thymol. In mixed populations of avian crop and cecal microbes, C. jejuni survivability was reduced 1.41 to 2.32 log_10 CFU mL-1 whether treated with thymol or β-D-thymol. Thymol and β-D-thymol inhibited ammonia accumulation in mixed populations of porcine and mixed bovine fecal microbes which is consistent with free thymol's purported role as a deaminase inhibitor. Conversely, thymol and β-D-thymol did not affect ammonia accumulation in mixed populations of avian gut microbes implicating population specific effects of these compounds. β-D-thymol, but not thymol, reduced accumulation of fermentation acids indicating the conjugate inhibited fermentation…
  note: by Sharon Epps.
  note: "Major Subject: Toxicology"
  note: Includes vita.
  note: Master of Science Texas A & M University 2013 http://hdl.handle.net/1969.1/151051
  note: Includes bibliographical references.
  note: Text (Thesis)
  subject:
    topic: Major Toxicology
  subject:
    topic: Campylobacter
  subject:
    topic: Antimicrobial
  subject:
    topic: Bactericidal
  subject:
    topic: Guillian Barre Syndrome
  subject:
    topic: Thymol-β-D-Glucopyranosid
  identifier: http://hdl.handle.net/1969.1/151051
  record info:
    record content source: TXA
    record creation date: 140226
    record change date: 20151206092155.0
    record identifier: in00003434102
    language of cataloging:
      language term: eng