rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Evaluation of Sediment Toxicity Using a Suite of Assessment Tools
  name:
    name part: Kelley, Matthew Allen
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: McDonald, Thomas
    role:
      role term: thesis advisor.
  name:
    name part: Texas A & M University
    role:
      role term: degree granting institution.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: txu
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource.
  abstract: Accurate characterization of risk of adverse ecological effects related to contaminated sediment presents a particularly difficult challenge. A series of studies has been conducted to investigate the utility of various tools for assessment of sediment toxicity. The goal of this research was to provide information which could help increase the accuracy with which predictions of toxicity could be made at hazardous sites. A calibration study was conducted using model PAHs, PCBs, a binary PAH mixture and a coal-tar mixture. This study was a collaborative effort among five university-based Superfund Research Programs (SRPs). Each program, with the help of funding through the NIEHS Superfund Research Program, has developed a chemical-class specific assay to estimate toxicity of contaminants in sediment. This suite of bioassays expands the range of data typically obtained through the use of standard aquatic toxicity assays. A series of caged in situ exposure studies has been conducted using juvenile Chinook salmon and Pacific staghorn sculpin in the Lower Duwamish Waterway. The study aimed to investigate the utility of selected biomarkers in evaluating the relationship between contaminants present in environmental samples and response in receptors following an in situ caged exposure. Results found that DNA adducts detected in exposed fish were significantly higher than controls in 2004 and 2006, and DNA adducts appear to be a reliable indicator of exposure, although no dose-response relationship was present. Western blot analysis of CYP1A1 was not indicative of exposure levels. The final study conducted was concerned with evaluating the utility of using solid phase microextraction (SPME) fibers in situ to evaluate contaminated sediment. Levels of PAHs and PCBs in sediment often exceeded sediment quality guidelines; however, results from aquatic toxicity bioassays using Hyalella azteca were mostly negative, thus levels of contaminants detected on SPME fibers could not be as…
  note: by Matthew Allen Kelley.
  note: "Major Subject: Toxicology"
  note: Includes vita.
  note: Doctor of Philosophy Texas A & M University 2010 http://hdl.handle.net/1969.1/149206
  note: Includes bibliographical references.
  note: Text (Dissertation)
  subject:
    topic: Major Toxicology
  subject:
    topic: Sediment
  subject:
    topic: PAHs
  subject:
    topic: PCBs
  subject:
    topic: DNA adducts
  subject:
    topic: Solid Phase Microextraction
  subject:
    topic: SPME
  identifier: http://hdl.handle.net/1969.1/149206
  record info:
    record content source: TXA
    record creation date: 140127
    record change date: 20151206091318.0
    record identifier: in00003428738
    language of cataloging:
      language term: eng