rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Barium Titanate Nanoparticles as Exogenous Contrast Agents in Second Harmonic Optical Coherence Tomography
  name:
    name part: Pearson, Jeremy Taylor
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Applegate, Brian
    role:
      role term: thesis advisor.
  name:
    name part: Texas A & M University
    role:
      role term: degree granting institution.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: txu
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource.
  abstract: I propose and demonstrate a method by which barium titanate nanoparticle clusters can be used as exogenous contrast agents in Second Harmonic Optical Coherence Tomography imaging systems to localize and highlight desired regions of tissue. SH-OCT has previously been used to identify collagen within OCT images. However, SH-OCT signals from collagen are highly susceptible to inferior reflector artifacts because most of the second harmonic generated light is forward scattered. Second harmonic generating nanoparticle clusters exhibit high scattering properties, which can give them the advantage of backscattering a large quantity of second harmonic light while attenuating the forward scattered light. In this research project, a mathematical model is proposed in which the backward to forward scattering ratio of second harmonic generated light from nanoparticle layers is exponentially proportional to the thickness of the layer. This model was supported by measurements of the backward to forward scattering ratio of second harmonic light in barium titanate nanoparticles layers. This indicates that nanoparticle clusters can be designed and manufactured with the proper thickness so that they generate a large second harmonic signal without creating inferior reflector artifacts. The electronic version of this dissertation is accessible from http://hdl.handle.net/1969.1/149506
  note: by Jeremy Taylor Pearson.
  note: "Major Subject: Biomedical Engineering"
  note: Includes vita.
  note: Master of Science Texas A & M University 2013 http://hdl.handle.net/1969.1/149506
  note: Includes bibliographical references.
  note: Text (Thesis)
  subject:
    topic: Major Biomedical Engineering
  subject:
    topic: Optical Coherence Tomography
  subject:
    topic: Second Harmonic
  subject:
    topic: Second Harmonic Generation
  subject:
    topic: Optics
  subject:
    topic: Medical Imaging
  subject:
    topic: Non-linear Optics
  identifier: http://hdl.handle.net/1969.1/149506
  record info:
    record content source: TXA
    record creation date: 140117
    record change date: 20151206091204.0
    record identifier: in00003426012
    language of cataloging:
      language term: eng