rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Investigation of Nanoparticles for Use in Microwave Systems in Biomedicine
  name:
    name part: Taghavi, Houra
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Meissner, Kenith
    role:
      role term: thesis advisor.
  name:
    name part: Texas A & M University
    role:
      role term: degree granting institution.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: txu
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource.
  abstract: This research focuses on the microwave properties of nanoparticles for use as contrast and hyperthermia agents. Currently, visible light is used for irradiation of nanoparticles as hyperthermia agents. Additionally, visible/Near-infrared light is used for photoacoustic tomography (PAT) imaging. Compared to optical wavelengths, frequencies in microwave range transmit through tissue with high penetration depth. Thus, deep cancerous cells and malignant tissue may be treated and imaged. These nanoparticles could enable the use of a hybrid microwave/acoustic technique known as thermoacoustic tomography. Here, quantitative measurements of the heat generation in super paramagnetic iron oxide nanoparticle (SPIONs), gold nanoparticles (AuNPs), and gold nanoclusters (AuNCs) induced by microwave energy at 3 GHz, are presented and compared. Based on our experiments, SPIONs are the most efficient nanoparticles for microwave heating. Very high concentrations of SPIONs are able to convert microwave energy into heat about 22° C more than DI-water. AuNPs, which support plasmon resonances, do not provide heat under microwave irradiation as predicted by our computational analysis based on Mie Theory. AuNCs are a new form of ultra-small (<2.5 nm) AuNPs which do not support plasmonic resonances and have supra-molecular properties such as sub-conduction band transitions. Interestingly, AuNCs have the potential to absorb microwave energy and may provide an alternative to SPIONs. These nanoparticles had not yet been studied before in this frequency region. In addition, the absorption coefficient of nanoparticles were calculated using complex permittivity data from a dip probe kit and a Vector Network Analyzer (VNA) in a broad band range from 500 MHZ to 10 GHz. This method allows identification of best frequency region with highest penetration depth. In the last step, the nanoparticles with different concentrations were tested as exogenous contrast agents in a Thermoacoustic Tomography (TAT…
  note: by Houra Taghavi.
  note: "Major Subject: Biomedical Engineering"
  note: Includes vita.
  note: Master of Science Texas A & M University 2013 http://hdl.handle.net/1969.1/149496
  note: Includes bibliographical references.
  note: Text (Thesis)
  subject:
    topic: Major Biomedical Engineering
  subject:
    topic: Gold nanoparticles (AuNPs)
  subject:
    topic: Gold nanoclusters (AuNCs)
  subject:
    topic: Super paramagnetic iron oxide nanoparticles (SPIONs)
  subject:
    topic: Microwave irradiation
  identifier: http://hdl.handle.net/1969.1/149496
  record info:
    record content source: TXA
    record creation date: 140117
    record change date: 20151206091202.0
    record identifier: in00003425998
    language of cataloging:
      language term: eng