Oxidation of amino acids, peptides, and proteins : kinetics and mechanism /
This book summarizes the chemical mechanisms and detailed kinetics of amino acid and peptide oxidation to help understand how proteins break down or dissociate when under stress in biological and environmental systems so that new drugs and antioxidants may be developed. It provides a summary of fund...
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| Format: | eBook |
| Language: | English |
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Hoboken, N.J. :
Wiley,
[2013]
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| Series: | Wiley series on reactive intermediates in chemistry and biology ;
v. 5. |
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| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Title page; Copyright page; Dedication; Contents; Preface to Series; Introduction; 1: Reactive Species; 1.1 Diseases; 1.1.1 Neurodegenerative Diseases; 1.1.2 Metals in Human Diseases; 1.2 Protein Structure; 1.2.1 Oxidative Labeling; 1.2.2 Other Techniques; 1.3 Reactive Species; 1.3.1 Halogen Species; 1.3.2 Oxygen Species; 1.3.3 Nitrogen Species; 1.3.4 Sulfur Species; 1.3.5 High-Valent Cr, Mn, and Fe Species; 1.4 Reactive Species in Environmental Processes; 1.4.1 Atmospheric Environment; 1.4.2 Disinfection By-Products (DBP); 1.4.3 Oxidation Processes for Purifying Water; References.2: Acid-Base Properties2.1 Dissociation Constants; 2.2 Speciation; 2.2.1 Protonation; 2.2.2 Metal Complexes; References; 3: Halogenated Species; 3.1 Hypohalogens; 3.1.1 Hypochlorite; 3.1.2 Hypobromite; 3.1.3 Hypothiocyanous; 3.2 Halamines; 3.2.1 Hydrolysis of Halamines; 3.2.2 Halogen Transfer by Halamines; 3.2.3 Reduction of Halamines; 3.3 Chlorine Dioxide; 3.3.1 Generation of ClO2; 3.3.2 Decomposition of ClO2; 3.3.3 Reactivity of ClO2; 3.4 Conclusions; References; 4: Reactive Oxygen Species; 4.1 Superoxide; 4.1.1 Generation; 4.1.2 Properties; 4.1.3 Reactivity; 4.1.4 Metalloenzymes.
- 4.2 Singlet Oxygen4.2.1 Reactivity; 4.3 Ozone; 4.3.1 Reactivity; 4.4 Hydroxyl Radical; 4.4.1 Generation; 4.4.2 Reactivity; 4.5 Conclusions; References; 5: Reactive Inorganic Oxy-Species of C, N, S, and P; 5.1 Carbon Species; 5.1.1 Carbonate Radical; 5.1.2 Peroxymonocarbonate; 5.1.3 Carboxyl Radical; 5.2 Nitrogen Species; 5.2.1 Nitrogen Monoxide; 5.2.2 Nitrogen Dioxide Radical; 5.2.3 Peroxynitrite; 5.3 Sulfur Species; 5.3.1 Oxysulfur Radicals; 5.4 Phosphorous Species; 5.4.1 Phosphate Radicals; 5.5 Conclusions; References; 6: High-Valent Cr, Mn, and Fe Species; 6.1 Chromium.6.1.1 Aqueous Chemistry of Oxo-Cr Compounds6.1.2 Chromium(VI, V, and IV) Complexes; 6.1.3 Reduction of Cr(VI/V/IV) by Substrates; 6.1.4 Reactivity of Cr Species; 6.1.5 Mechanism; 6.1.6 Carcinogenesis; 6.1.7 Genotoxicity and Cytotoxicity; 6.1.8 Conclusions; 6.2 Manganese; 6.2.1 Aqueous Chemistry of Oxo-Mn Compounds; 6.2.2 Reactivity of Complexes of Hypervalent Mn; 6.2.3 Oxidation by Mn(VII); 6.2.4 Conclusions; 6.3 Iron; 6.3.1 Iron(IV) and Iron(V); 6.3.2 Reactivity of Ferrate(V) and Ferrate(VI); 6.3.3 Conclusions; References; Index.