Oxidation of amino acids, peptides, and proteins : kinetics and mechanism /

This book summarizes the chemical mechanisms and detailed kinetics of amino acid and peptide oxidation to help understand how proteins break down or dissociate when under stress in biological and environmental systems so that new drugs and antioxidants may be developed. It provides a summary of fund...

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Bibliographic Details
Main Author: Sharma, Virender K.
Corporate Author: Ebook Library
Other Authors: Rokita, Steven E.
Format: eBook
Language:English
Published: Hoboken, N.J. : Wiley, [2013]
Series:Wiley series on reactive intermediates in chemistry and biology ; v. 5.
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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100 1 |a Sharma, Virender K. 
245 1 0 |a Oxidation of amino acids, peptides, and proteins :  |b kinetics and mechanism /  |c Virender K. Sharma. 
264 1 |a Hoboken, N.J. :  |b Wiley,  |c [2013] 
264 4 |c ©2013 
300 |a 1 online resource (xvii, 401 pages, 12 unnumbered pages of plates :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Wiley series on reactive intermediates in chemistry and biology ;  |v v. 5 
505 8 |a Title page; Copyright page; Dedication; Contents; Preface to Series; Introduction; 1: Reactive Species; 1.1 Diseases; 1.1.1 Neurodegenerative Diseases; 1.1.2 Metals in Human Diseases; 1.2 Protein Structure; 1.2.1 Oxidative Labeling; 1.2.2 Other Techniques; 1.3 Reactive Species; 1.3.1 Halogen Species; 1.3.2 Oxygen Species; 1.3.3 Nitrogen Species; 1.3.4 Sulfur Species; 1.3.5 High-Valent Cr, Mn, and Fe Species; 1.4 Reactive Species in Environmental Processes; 1.4.1 Atmospheric Environment; 1.4.2 Disinfection By-Products (DBP); 1.4.3 Oxidation Processes for Purifying Water; References.2: Acid-Base Properties2.1 Dissociation Constants; 2.2 Speciation; 2.2.1 Protonation; 2.2.2 Metal Complexes; References; 3: Halogenated Species; 3.1 Hypohalogens; 3.1.1 Hypochlorite; 3.1.2 Hypobromite; 3.1.3 Hypothiocyanous; 3.2 Halamines; 3.2.1 Hydrolysis of Halamines; 3.2.2 Halogen Transfer by Halamines; 3.2.3 Reduction of Halamines; 3.3 Chlorine Dioxide; 3.3.1 Generation of ClO2; 3.3.2 Decomposition of ClO2; 3.3.3 Reactivity of ClO2; 3.4 Conclusions; References; 4: Reactive Oxygen Species; 4.1 Superoxide; 4.1.1 Generation; 4.1.2 Properties; 4.1.3 Reactivity; 4.1.4 Metalloenzymes. 
505 8 |a 4.2 Singlet Oxygen4.2.1 Reactivity; 4.3 Ozone; 4.3.1 Reactivity; 4.4 Hydroxyl Radical; 4.4.1 Generation; 4.4.2 Reactivity; 4.5 Conclusions; References; 5: Reactive Inorganic Oxy-Species of C, N, S, and P; 5.1 Carbon Species; 5.1.1 Carbonate Radical; 5.1.2 Peroxymonocarbonate; 5.1.3 Carboxyl Radical; 5.2 Nitrogen Species; 5.2.1 Nitrogen Monoxide; 5.2.2 Nitrogen Dioxide Radical; 5.2.3 Peroxynitrite; 5.3 Sulfur Species; 5.3.1 Oxysulfur Radicals; 5.4 Phosphorous Species; 5.4.1 Phosphate Radicals; 5.5 Conclusions; References; 6: High-Valent Cr, Mn, and Fe Species; 6.1 Chromium.6.1.1 Aqueous Chemistry of Oxo-Cr Compounds6.1.2 Chromium(VI, V, and IV) Complexes; 6.1.3 Reduction of Cr(VI/V/IV) by Substrates; 6.1.4 Reactivity of Cr Species; 6.1.5 Mechanism; 6.1.6 Carcinogenesis; 6.1.7 Genotoxicity and Cytotoxicity; 6.1.8 Conclusions; 6.2 Manganese; 6.2.1 Aqueous Chemistry of Oxo-Mn Compounds; 6.2.2 Reactivity of Complexes of Hypervalent Mn; 6.2.3 Oxidation by Mn(VII); 6.2.4 Conclusions; 6.3 Iron; 6.3.1 Iron(IV) and Iron(V); 6.3.2 Reactivity of Ferrate(V) and Ferrate(VI); 6.3.3 Conclusions; References; Index. 
520 |a This book summarizes the chemical mechanisms and detailed kinetics of amino acid and peptide oxidation to help understand how proteins break down or dissociate when under stress in biological and environmental systems so that new drugs and antioxidants may be developed. It provides a summary of fundamental information on the kinetics and mechanism of amino acids by various oxidants. It also discusses oxidative chemistry of amino acids, peptides, and proteins. This useful guide also provides problems and their solutions associated with amino acids, peptides, and proteins in the aquatic environment. 
588 |a Description based on print version record. 
500 |a Electronic resource. 
650 4 |a Amino Acids  |x metabolism. 
650 4 |a Environmental Pollutants  |x chemistry. 
650 4 |a Oxidation-Reduction. 
650 4 |a Peptides  |x metabolism. 
650 4 |a Proteins  |x metabolism. 
650 0 |a Proteins  |x Metabolism. 
650 0 |a Oxidation-reduction reaction. 
650 0 |a Amino acids  |x Metabolism. 
650 0 |a Environmental toxicology. 
650 0 |a Peptides  |x Metabolism. 
650 0 |a Amino acids  |x Oxidation. 
650 0 |a Peptides  |x Oxidation. 
650 0 |a Proteins  |x Oxidation. 
655 7 |a Electronic books.  |2 local 
700 1 |a Rokita, Steven E. 
710 2 |a Ebook Library. 
776 0 8 |i Print version:  |a Sharma, Virender K.  |t Oxidation of Amino Acids, Peptides, and Proteins : Kinetics and Mechanism  |d Chicester : Wiley, c2012  |z 9780470627761 
830 0 |a Wiley series on reactive intermediates in chemistry and biology ;  |v v. 5. 
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952 f f |a Texas A&M University  |b College Station  |c Electronic Resources  |d Available Online  |t 0  |e QD431 .S537 2013eb  |h Library of Congress classification 
998 f f |a QD431 .S537 2013eb  |t 0  |l Available Online