rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Relative damaging ability of galactic cosmic rays determined using Monte Carlo simulations of track structure
  name:
    name part: Cox, Bradley.
    role:
      role term: creator
  name:
    name part: Braby, Leslie A.
    role:
      role term: thesis advisor.
  name:
    name part: Guetersloh, Stephen B.
    role:
      role term: thesis advisor.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: txu
    date issued: 2012
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource.
  abstract: The energy deposition characteristics of heavy ions vary substantially compared to those of photons. Many radiation biology studies have compared the damaging effects of different types of radiation to establish relative biological effectiveness among them. These studies are dependent on cell type, biological endpoint, radiation type, dose, and dose rate. The radiation field found in space is much more complicated than that simulated in most experiments, both from a point of dose-rate as well as the highly mixed field of radiative particles encompassing a broad spectrum of energies. To establish better estimates for radiation risks on long-term, deep space missions, the damaging ability of heavy ions requires further understanding. Track structure studies provide significant details about the spatial distribution of energy deposition events in and around the sensitive targets of a mammalian cell. The damage imparted by one heavy ion relative to another can be established by modeling the track structures of ions that make up the galactic cosmic ray (GCR) spectrum and emphasizing biologically relevant target geometries. This research was undertaken to provide a better understanding of the damaging ability of GCR at the cellular level. By comparing ions with equal stopping power values, the differences in track structure will illuminate variations in cell particle traversals and ionization density within cell nuclei. For a cellular target, increased particle traversals, along with increased ionization density, are key identifiers for increased damaging ability. Performing Monte Carlo simulations with the computer code, FLUKA, this research will provide cellular dosimetry data and detail the track structure of the ions. As shown in radiobiology studies, increased ionizations within a cell nucleus generally lead to increased DNA breaks and increased free radical production, resulting in increased carcinogenesis and cell death. The spatial distribution of dose surrounding…
  note: by Bradley William Cox.
  note: "Major Subject: Nuclear Engineering"
  note: Electronic resource.
  note: Doctor of Philosophy Texas A&M University 2011 http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-10105
  note: Includes bibliographical references.
  note: Text (Dissertation)
  subject:
    topic: Major Nuclear Engineering
  subject:
    topic: Galactic Cosmic Rays
  subject:
    topic: Delta Ray
  subject:
    topic: Quality Factor
  subject:
    topic: Space radiation
  subject:
    topic: Track Structure
  subject:
    topic: FLUKA
  identifier: http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-10105
  record info:
    record content source: TXA
    record creation date: 121120
    record change date: 20150922145158.0
    record identifier: in00002785137