rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Three dimensional simulation of Rayleigh-Bénard convection for rapid microscale polymerase chain reaction
  name:
    name part: Muddu, Radha Malini Gowri.
    role:
      role term: creator
  name:
    name part: Ugaz, Victor M.
    role:
      role term: thesis advisor.
  name:
    name part: Hassan, Y. A.
    role:
      role term: thesis advisor.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: txu
    date issued: 2012
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource.
  abstract: Rayleigh-Bénard convection has been extensively studied in literature owing to its ubiquitous nature. However, most of the studies have been confined to geometries where the aspect ratio of the cylinder was less than 1. Here we study the motion of fluid in geometries with aspect ratio greater than 1, with particular application to use of such motion to actuate biochemical reactions, such as the polymerase chain reaction. We show that it is possible to accelerate the rate of reaction by using a geometry that promotes chaotic motion versus a geometry that promotes quasi- periodic motion. We also simulate chemical kinetics using the fluid motion as a starting point and we prove that chaotic motion indeed enhances the rate of the reaction. We also provide qualitative and quantitative measures for chaotic motion in a fluid flow, which helps to distinguish between different types of fluid motion. We highlight the transitions between different types of flow that are possible with Rayleigh-Bénard convection. Finally, we compare our simulations against experimental data obtained from particle image velocimetry, laser induced fluorescence and optical microscopic visualization.
  note: by Radha Malini Gowri Muddu.
  note: "Major Subject: Mechanical Engineering"
  note: Electronic resource.
  note: Doctor of Philosophy Texas A&M University 2010 http://hdl.handle.net/1969.1/ETD-TAMU-2010-12-8780
  note: Includes bibliographical references.
  note: Text (Dissertation)
  subject:
    topic: Major mechanical engineering
  subject:
    topic: polymerase chain reaction
  subject:
    topic: Rayleigh-Bénard convection
  identifier: http://hdl.handle.net/1969.1/ETD-TAMU-2010-12-8780
  record info:
    record content source: TXA
    record creation date: 120320
    record change date: 20151202151856.0
    record identifier: in00002742130