Medicinal chemistry of nucleic acids /

Covering all areas of the medicinal chemistry and therapeutic applications of nucleic acids, this book provides up-to-date coverage of the broad area of nucleic acid chemistry and biology. The book lays out the basic principles of medicinal chemistry of nucleic acids before focusing on the developme...

Full description

Bibliographic Details
Other Authors: Chattopadhyaya, Jyoti, Xi, Zhen, Zhang, Li-He
Format: eBook
Language:English
Published: Hoboken, N.J. : John Wiley & Sons, [2011]
Series:Wiley online library.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Recent advances in carbocyclic nucleosides : synthesis and biological activity / Jianing Wang, Ravindra K. Rawal, and Chung K. Chu
  • Structures and functions of nucleic acids modified with S, Se, and Teand complexed with small molecules / Wen Zhang, Jia Sheng, and Zhen Huang
  • Unraveling of the NAD cyclizing and calcium signaling functions of human CD38 / Hon Cheung Lee
  • DNA and RNA binding small molecules / Shibo Li and Zhen Xi
  • G-quadruplex DNA and its ligands in anticancer therapy / Zhi-shu Huang ... [et al.]
  • Molecular modeling in nucleic acid targeted drug design / Lidan Sun ... [et al.]
  • Structure of 10-23 DNAzyme in complex with the target RNA in silico : a progress report on the mechanism of RNA cleavage by DNA enzyme / Oleksandr Plashkevych and Jyoti Chattopadhyaya
  • Labeling oligonucleotides towards the biomedical probe / Il Joon Lee and Byeang Hyean Kim
  • Locked nucleic acid oligonucleotides towards clinical application / Rakesh N. Veedu and Jesper Wengel
  • The pharmacokinetics researches of nucleic acid drugs / Shengqi Wang
  • Inducible RNAi and drug target validation / Wei Xiong ... [et al.]
  • SiRNA : the specificity and off-target effects
  • Quan Du, Huang Huang, Zicai Liang.