Lead generation approaches in drug discovery /

Bibliographic Details
Other Authors:	Ranković, Zoran, Morphy, Richard
Format:	eBook
Language:	English
Published:	Hoboken, N.J. : John Wiley, [2010]
Series:	Wiley online library.
Subjects:	Drug development. Drugs > Design. High throughput screening (Drug development) Drug Discovery > methods. Lead. MEDICAL > Drug Guides. MEDICAL > Pharmacology. MEDICAL > Pharmacy. MEDICAL > Nursing > Pharmacology. Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

Lead discovery : the process / William F. Michne
High throughput screening approach to lead discovery / Zoran Rankovic, Craig Jamieson, and Richard Morphy
In silico screening / Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath
Fragment-based lead discovery / Jeffrey S. Albert
Design of multitarget ligands / Richard Morphy and Zoran Rankovic
De novo drug design / Gisbert Schneider, Markus Hartenfeller, Ewgenij Proschak
Role of natural products in drug discovery / Hugo Lachance, Stefan Wetzel, and Herbert Waldmann
Early screening for ADMET properties / Dennis A. Smith
Role of chemistry in lead discovery / Roland E. Dolle and Karin Worm.