Cover Image

Review of the Environmental Protection Agency's draft IRIS assessment of tetrachloroethylene /

Tetrachloroethylene is a volatile, chlorinated organic hydrocarbon that is widely used as a solvent in the dry-cleaning and textile-processing industries and as an agent for degreasing metal parts. It is an environmental contaminant that has been detected in the air, groundwater, surface waters and...

Full description

Bibliographic Details
Corporate Authors: National Research Council (U.S.). Committee to Review EPA's Toxicological Assessment of Tetrachloroethylene, United States. Environmental Protection Agency, National Academies Press (U.S.)
Format: Book
Language:English
Published: Washington, D.C. : National Academies Press, [2010]
Subjects:
Tetrachloroethylene > toxicity.
Environmental Exposure.
Risk Assessment.
Tetrachloroethylene > Risk assessment.
Tetrachloroethylene > Toxicology.
Online Access:http://www.nap.edu/catalog.php?record%5Fid=12863
http://www.nap.edu/catalog.php?record_id=12863
Table of Contents:
  • Introduction
  • Overview of the toxicokinetics of tetrachloroethylene
  • Neurotoxicity
  • Reproductive and developmental effects
  • Genotoxicity
  • Hepatic toxicity and cancer
  • Renal toxicity and cancer
  • Hematopoietic effects
  • General review of epidemiologic evidence pertaining to cancer
  • Reference values for tetrachloroethylene
  • Cancer risk estimates for tetrachloroethylene
  • Moving beyond the current state of practice.