rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Current trends in monoclonal antibody development and manufacturing
  name:
    name part: Shire, Steven J.
  name:
    name part: American Association of Pharmaceutical Scientists
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: nyu
    date issued: 2010
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: xiv, 351 pages : illustrations (some color) ; 27 cm.
  table of contents: 1. Introduction / Wayne R. Gombotz and Steven J. Shire -- pt. I. Design of therapeutic MABS. 2. CDR repair: a novel approach to antibody humanization / Mark S. Dennis -- 3. Nanobodies, single-domain antigen-binding fragments of camelid heavy-chain antibodies / Gholamreza Hassanzadeh Ghassabeh, Serge Muyldermans, and Dirk Saerens -- pt. II. Expression and production of MABS. 4. GPEx® a flexible method for the rapid generation of stable, high expressing, antibody producing mammalian cells lines / Gregory T. Bleck -- 5. Advancing our cell culture platform: incorporating lessons learned and new technologies / Carole Heath -- pt. III. Recovery and purification. 6. Addressing changes associated with technology transfer: a case study / Michele M. Myers ... [et al.] -- 7. Concepts for disposables in biopharmaceutical manufacture / Joachim K. Walter and Uwe Gottschalk -- pt. IV. Formulation and delivery. 8. Formulation and delivery issues for monoclonal antibody therapeutics / Ann L. Daugherty and Randall J. Mrsny -- 9. Challenges in the development of high protein concentration formulations / Steven J. Shire, Zahra Shahrock, and Jun Liu.
  table of contents: 10. Protein immobilization by crystallization and precipitation: an alternative to lyophilization / Karoline Bechtold-Peters -- pt. V. Analytics and specification setting for MABS. 11. Characterizing high affinity antigen/antibody complexes by kinetic and equilibrium based methods / Andrew W. Drake, David G. Myszka, and Scott L. Klakamp -- 12. Analytical characterization of monoclonal antibodies: linking structure to function / Reed J. Harris ... [et al.] -- 13. Analysis of irreversible aggregation, reversible self-association and fragmentation of monoclonal antibodies by analytical ultracentrifugation / James D. Andya, Jun Liu, and Steven J. Shires -- 14. Biophysical signatures of monoconal antibodies / N. Harn ... [et al.] -- pt. VI. Pharmacokinetics and immunogenicity. 15. Impact of Fc glycosylation on monoclonal antibody effector functions and degradation by proteases / T. Shantha Raju -- 16. Immunogenicity assessment of antibody therapeutics / P. stas, Y. Gansemans, and I. Lasters -- pt. VII. Armed antibodies and new classes of antibodies. 17. Production of monoclonal antibodies in E. coli / Dorothea E. Reilly and Daniel G. Yansura -- 18. Recent advances in the use of antibody drug conjugates for cancer theapy / Peter D. Senter -- 19. Antibody radiolabeling / Corinne Bensimon and Russell Redshaw.
  note: edited by Steven J. Shire [and others].
  note: Electronic resource.
  note: Electronic reproduction. New York : Springer, 2010. Mode of access: World Wide Web. System requirements: Web browser. Title from title screen (viewed on Aug. 9, 2010). Access may be restricted to users at subscribing institutions.
  note: Includes bibliographical references and index.
  subject:
    topic: Antibodies, Monoclonal
    topic: biosynthesis
  subject:
    topic: Antibodies, Monoclonal
    topic: analysis
  subject:
    topic: Antibodies, Monoclonal
    topic: pharmacokinetics
  subject:
    topic: Biotechnology
    topic: methods
  subject:
    topic: Monoclonal antibodies
  classification: QR186.85
  classification: 571.96
  classification: 2010 C-687
  classification: QW 575.5.A6 C976 2010
  related item:
    identifier: (DLC) 2009938432
    identifier: (OCoLC)496951432
  related item:
    title info:
      title: Biotechnology (Arlington, Va.) ; v. 11
  identifier: 038776643X
  identifier: 9780387766430
  identifier: 978-0-387-76642-3 Springer
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: GW5XE
    record creation date: 100909
    record change date: 20210727154940.0
    record identifier: in00002653800
    language of cataloging:
      language term: eng