Death receptors and cognate ligands in cancer /

Bibliographic Details
Other Authors:	Kalthoff, Holger
Format:	eBook
Language:	English
Published:	Heidelberg ; New York : Springer, [2009]
Series:	Results and problems in cell differentiation ; 49.
Subjects:	Receptors, Tumor Necrosis Factor > physiology. Neoplasms > etiology. Neoplasms > therapy. Receptors, Death Domain > physiology. Cancer > Treatment. Carcinogenesis > Molecular aspects. Cell receptors > Physiological effect. Tumor necrosis factor > Physiological effect. Tumor necrosis factor > Receptors > Physiological effect. Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

The role of TNF in cancer / Harald Wajant
Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses / Madhu Ramaswamy ... [et al.]
FasL expression and reverse signaling / M. Lettau ... [et al.]
Impact of TNF-R1 and CD95 internalization on apoptotic and antiapoptotic signaling / Stefan Schütze and Wulf Schneider-Brachert
Ubiquitination and TNFR1 signaling / Ken-ichi Fujita and Srinivasa M. Srinivasula
From biochemical principles of apoptosis induction by TRAIL to application in tumour therapy / Stefanie M. Cordier, Kerstin Papenfuss, and Henning Walczak
Therapeutic targeting of TWEAK/Fn14 in cancer: exploiting the intrinsic tumor cell killing capacity of the pathway / Jennifer S. Michaelson and Linda C. Burkly
APRIL in B-cell malignancies and autoimmunity / Fiona C. Kimberly, Jan Paul Medema, and Michael Hahne
Autophagy in cancer and chemotherapy / Shida Yousefi and Hans-Uwe Simon
Glucocorticoid-mediated apoptosis resistance of solid tumors / Ingrid Herr, Markus W. Büchler, and Jürgen Mattern
Targeting death-receptors in radiation therapy / Olivier Niemöller and Claus Belka
Death ligands designed to kill: development and application of targeted cancer therapeutics based on proapoptotic TNF family ligands / Jeannette Gerspach, Harald Wajant, and Klaus Pfizenmaier.