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Label-free technologies for drug discovery /

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Bibliographic Details
Other Authors: Cooper, M. A. (Matthew A.), Mayr, Lorenz
Format: eBook
Language:English
Published: Chichester, West Sussex, U.K. : John Wiley & Sons, 2011.
Series:Wiley online library.
Subjects:
Drug development.
Drug Discovery.
Biosensing Techniques.
Drug Design.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Matter
  • The Revolution of Real-Time, Label-Free Biosensor Applications / Rebecca L Rich, David G Myszka
  • Design and Implementation of Vertically Emitting Distributed Feedback Lasers for Biological Sensing / Meng Lu, Steven S Choi, Chun Ge, Clark J Wagner, J Gary Eden, Brian T Cunningham
  • SPR Screening of Chemical Microarrays for Fragment-Based Discovery / Thomas Neumann, Renate Sekul
  • The CellKeyʼ System: A Label-Free Cell-Based Assay Platform for Early Drug Discovery Applications / Ryan P McGuinness, Debra L Gallant, Yen-Wen Chen, Trisha A Tutana, Donna L Wilson, John M Proctor, H Roger Tang
  • Dynamic and Label-Free Cell-Based Assays Using the xCELLigence System / Yama A Abassi, Alexander Sieler, Manfred Watzele, Xiaobo Wang, Xiao Xu
  • Selecting the Best HTS Hits to Move Forward: ITC Ligand Binding Characterization Provides Guidance / Ronan O'Brien, Richard Brown
  • Incorporating Transmitted Light Modalities into High-Content Analysis Assays / Robert Graves
  • Nonradioactive Rubidium Efflux Assay Technology for Screening of Ion Channels / Georg C Terstappen
  • Expanding the Scope of HTMS Methods / Tom G Holt, Jun Wang, Xun Chen, Bernard K Choi, Neil S Geoghagen, Kristian K Jensen, Maxine Jonas, Qi Luo, William A LaMarr, Lorraine Malkowitz, Can C Ozbal, Yusheng Xiong, Claude Dufresne, Ming-Juan Luo
  • A Novel Multiplex SPR Array for Rapid Screening and Affinity Determination of Monoclonal Antibodies: The ProteOn XPR36 Label Free System: Kinetic Screening of Monoclonal Antibodies / Vered Bronner, Oded Nahshol, Tsafrir Bravman
  • Biophysics/Label-Free Assays in Hit Discovery and Verification / Johannes Ottl
  • Harnessing Optical Label-Free on Microtiter Plates for Lead Finding: From Binding to Phenotypes / Julio Martin
  • Use of Label-Free Detection Technologies in the Hit-to-Lead Process: Surface Optical Detection of Cellular Processes / F Stuhmeier, J Bradley, E Fairman, E Gbekor, P Hayter, S Ramsey
  • Cellular Screening for 7TM Receptors Using Label-Free Detection / Jeffrey C Jerman, Jason Brown, Magalie Rocheville
  • Novartis Evaluation of the ForteBio Octet RED: A Versatile Instrument for Direct Binding Experiments / Eric Martin, John Wang, Isabel Zaror, Jiamin Yu, Kelly Yan, Mike Doyle, Paul Feucht, Kevin Shoemaker, Bob Warne, Mike Chin, Blisseth Sy, Lukas Leder, Marco Meyerhofer, Charles Wartchow, Danfeng Yao
  • The Pyramid₉ Approach to Fragment-Based Biophysical Screening / Glyn Williams
  • Characterisation of Antibodies Against the Active Conformation of G Using the SRU-BINDʼ Label-Free Detection System / Melanie Leveridge, Chun-Wa Chung, Trevor Wattam
  • SPR-Based Direct Binding Assays in Drug Discovery / Walter Huber
  • Kinetic Binding Mechanisms: Their Contribution to an Optimal Therapeutic Index / David C Swinney
  • ITC: More Than Just Binding Affinities / Ernesto Freire
  • Index.