http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
xii, 533 pages, 24 unnumbered pages of plates : illustrations (some color) ; 26 cm.
New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza.These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases explained by the evolutionary flexibility of the viral agents that circulate in a continuously changing earth environment. * NEW to this edition - chapters on the molecular basis of copying fidelity of viral polymerases, methods to establish phylogenetic relationships among viruses, and the mechanisms of cellular RNA interference and editing functions as they affect virus evolution. * UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups. * Bacterial, plant, animal and human viruses are compared regarding their interaction with their hosts.
Origins and widespread evolutionary significance of viruses; Nature and evolution of early replicons; Structure and evolution of viroids; Mutation, competition and selection as measured with small RNA molecules; Viral quasispecies, fitness variations and error;Phylogenetic analysis of viral sequences: principles and applications; Evolution of functional protein motifs in RNA viruses; Copying fidelity of viral and cellular polymerases; RNA interference and its evolutionary implications; Phage models of virus adaptation and evolution; Genomic analysis and evolution of large bacteriophages; Plant virus evolution: past, present and future; Mutant clouds and bottleneck events in plant virus evolution; Retrovirus evolution and pathogenesis; HIV population dynamics and drug treatments; The impact of rapid evolution of hepatitis viruses; Evolution of animal and human influenza viruses; Evolution and emergence of arboviruses; Parvovirus variation and evolution: impact on disease emergence; Genome diversity and evolution of human papillomaviruses; Poxvirus diversity and evolution; The molecular evolutionary history of the herpesviruses; Cellular functions involved in virual hypermutagenesis.
Early replicons / Peter Schuster, Peter F. Stadler -- Structure and evolution of viroids / Núria Duran-Vila, ... [et al.] -- Mutation, competition and selection as measured with small RND molecules / Christof K. Biebricher -- Viral quasispecies / Esteban Domingo, ... [et al.] -- Comparative studies of RNA virus evolution / Edward C. Homes -- Nucleic acid polymerase fidelity and viral population fitness / Eric D. Smidansky, Jamie J. Arnold, Craig E. Cameron -- Complex interactions of viruses and the RNAi machinery / Ronald P. van Rij, Raul Andino -- Role of the APOBEC3 family of cytidine deaminases in innate immunity, G-to-A hypermution and evolution of retroviruses / Mario L. Santiago, Warner C. Greene -- Lethal Mutagenesis / James J. Bull, Rafael Sanjuán, Claus O. Wilke -- Evolution of dsDNA tailed phages / Roger W. Hendrix -- More about plant virus evolution / Adrian Gibbs, ... [et al.] -- Mutant clouds and bottleneck evens in plant virus evolution / Marilyn J. Roossinck -- Retrovirus evolution / Sminon Wain-Hobston -- Intra-host dynamics and evolution of HIV infection / Viktor Müller, Sebastain Bonhoeffer -- Impact of rapid evolution of hepatitis viruses / J. Quer, ... [et al.] -- Arbovirus evolution / Kathryn A. Hanley, Scott C. Weaver / Evolution and variation of the parvoviruses / Karin Hoelzer, Colin R. Parrish -- Genome diversity and evolution of papillomaviruses / Hans-Ulrich Bernard -- Origin and evolution of poxviruses / John W. Barrett, Grant McFadden -- Molecular evolution of the Herpesvirales / Duncan J. McGeoch, ... [et al.] -- Widespread evolutionary significance of viruses / Luis P. Villarreal.
Electronic reproduction. Amsterdam : Elsevier Science & Technology, 2008. Mode of access: World Wide Web. System requirements: Web browser. Title from title screen (viewed on Nov. 14, 2008). Access may be restricted to users at subscribing institutions.
Includes bibliographical references and index.
141050:141192 Elsevier Science & Technology