Table of Contents:
  • Bioinformatics: mystery, astrology, or service technology? / Frank Eisenhaber
  • Reliable and specific protein function prediction by combining homology with genomic(s) context / Martijn A. Huynen, Berend Snel, and Toni Gabalden
  • Clues from three-dimensional structure analysis and molecular modelling: new insights into cytochrome P450 mechanisms and functions / Karin Schleinkofer and Thomas Dandekar
  • Prediction of protein function: two basic concepts and one practical recipe / Frank Eisenhaber
  • Extracting information for meaningful function inference through text-mining / Hong Pan ... [et al.]
  • Literature and genome data mining for prioritizing disease-associated genes / Carolina Perez-Iratxeta, Peer Bork, and Miguel A. Andrade
  • Model-based inference of transcriptional regulatory mechanisms from DNA microarray data / Harmen J. Bussemaker
  • The predictive power of molecular network modelling: case studies of predictions with subsequent experimental verification / Stefan Schuster, Edda Klipp, and Marko Marhl
  • Theory of early molecular evolution: predictions and confirmations / Edward N. Trifonov
  • Hitchhiking mapping: limitations and potential for the identification of ecologically important genes / Christian Schlötterer
  • Understanding the functional importance of human single nucleotide polymorphisms / Saurabh Asthana and Shamil Sunyaev
  • Correlations between quantitative measures of genome evolution, expression, and function / Yuri I. Wolf, Liran Carmel, and Eugene V. Koonin.