Table of Contents:
  • History and morphology of the lysosome / Renate Lüllmann-Rauch
  • Transport of lysosomal enzymes / Stephan Storch and Thomas Braulke
  • Adaptor proteins in lysosomal biogenesis / Peter Schu
  • Lysosomal membrane proteins / Paul Saftig
  • Lysosomal proteases: revival of the sleeping beauty / Klaudia Brix
  • Lysosomal storage disorders / Ole Kristian Greiner-Tollersrud and Thomas Berg
  • Lysosomal transporters and associated diseases / Frans W. Verheijen and Grazia M.S. Mancini
  • Neuronal ceroid-lipofuscinoses / Jaana Tyynelè
  • Cholesterol transport in lysosomes / Judith Storch and Sunita R. Cheruku
  • Therapy of lysosomal storage diseases / Ulrich Matzner
  • Lysosomal proteome and transcriptome / Jobst Landgrebe and Torben Lubke
  • External lysosomes: the osteoclast and its unique capacities / Vincent Everts and Wouter Beertsen
  • Membrane resealing mediated by lysosomal exocytosis / Norma W. Andrews
  • Macroautophagy in mammalian cells / Eeva-Liisa Eskelinen
  • Chaperone-mediated autophagy / Erwin Knecht and Natalia Salvador.