rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Histopathology of preclinical toxicity studies
    sub title: interpretation and relevance in drug safety evaluation
  name:
    name part: Greaves, P. (Peter)
    name part: M.B., Ch.B
    role:
      role term: creator
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: ne
    date issued: 2007
    edition: 3rd ed.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: remote
    extent: vii, 953 pages : color illustrations ; 25 cm.
  abstract: This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology. NEW TO THE THIRD EDITION: * Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies * General comments to each chapter about the relevance of pathological findings to humans * Provides essential information that can help decide the relevance of particular lesions for patients.
  table of contents: Introduction -- Integumentary System -- Mammary Gland -- Haemopoietic and Lymphatic Systems -- Musculoskeletal System -- Respiratory Tract -- Cardiovascular System -- Gastrointestinal tract.
  note: Peter Greaves.
  note: Electronic resource.
  note: Electronic reproduction. Amsterdam : Elsevier Science & Technology, 2007. Mode of access: World Wide Web. System requirements: Web browser. Title from title screen (viewed on July 25, 2007). Access may be restricted to users at subscribing institutions.
  note: Includes bibliographical references and index.
  subject:
    topic: Drug Evaluation, Preclinical
  subject:
    topic: Animals, Laboratory
  subject:
    topic: Histology
  subject:
    topic: Pathology
  subject:
    topic: Drugs
    topic: Toxicity testing
  subject:
    topic: Laboratory animals
    topic: Histopathology
  classification: RA1238 .G74 2007
  classification: 615.9
  classification: 2007 F-019
  classification: QV 771 G787h 2007
  related item:
    identifier: (OCoLC)123373759
  identifier: 9780444527714
  identifier: 0444527710
  identifier: 133525:133650 Elsevier Science & Technology
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: OPELS
    record creation date: 070802
    record change date: 20260609193331.0
    record identifier: in00002425986