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Hplc Method Development for Pharmaceuticals /

High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Meth...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Ahuja, Satinder, 1933-, Rasmussen, Henrik
Format: eBook
Language:English
Published: [Place of publication not identified] : Academic Pr, 2007.
Series:Separation science and technology (San Diego, Calif.) ; v. 8.
Subjects:
High performance liquid chromatography > Methodology.
Drugs > Analysis.
Drug development.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • 1. Overview (Satinder Ahuja).
  • 2. HPLC Theory (Y.V. Kazakevich).
  • 3. HPLC Columns and Packings (U.D. Neue <IT>et al</IT>.).
  • 4. Column Characterization and Selection (D. Visky).
  • 5. Chiral Separations (Xiande Wang <IT>et al</IT>.).
  • 6. Contemporary Liquid Chromatographic Systems for Method Development (M. Swartz).
  • 7. Hyphenated Techniques (D.L. Norwood <IT>et al</IT>.).
  • 8. HPLC Sample Preparation (G. Slack, N.H. Snow).
  • 9. Instrument and Software Qualification and Validation (D. Van Geel).
  • 10. Pharmaceutical Development: From Pre-clinical to Post Approval (K. Bynum).
  • 11. HPLC Method Development for Drug Discovery LC-MS Assays in Rapid PK Applications (Xiaoying Xu, W. Korfmacher).
  • 12. HPLC Method Development in Early Phase Pharmaceutical Development (H.T. Rasmussen <IT>et al</IT>.).
  • 13. HPLC Method Development in Late Phase Pharmaceutical Development (M. Ilias Jimidar).
  • 14. Use of HPLC for In-process Testing (C. Richardson).
  • 15. Method Development for Biomolecules (D.E. Raynie, J.L. Driver).
  • 16. Method Validation (M. Ilias Jimidar <IT>et al</IT>.).
  • 17. Troubleshooting HPLC Methods (H. McNair).
  • 18. Molecularly Imprinted Polymers as Sorbents for Separations and Extractions (M.T. Koesdjojo <IT>et al</IT>.).