Targeted interference with signal transduction events /

Bibliographic Details
Corporate Author:	SpringerLink (Online service)
Other Authors:	Groner, B. (Bernd)
Format:	eBook
Language:	English
Published:	Berlin ; New York : Springer, [2007]
Series:	Recent results in cancer research. v. 172.
Subjects:	Neoplasms > drug therapy. Cell Communication > physiology. Drug Delivery Systems. Neoplasms > physiopathology. Signal Transduction > physiology. Cancer > Chemotherapy. Cancer > Gene therapy. Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

Introduction: the rationale for the development of targeted drugs in cancer therapy
Identifying critical signaling molecules for the treatment of cancer
Tyrosine kinase inhibitors and cancer therapy
Targeting ERBB receptors in cancer
Inhibition of the IGF-I receptor for treatment of cancer. Kinase inhibitors and monoclonal anitbodies as alternative approaches
Inhibition of the TGF-B signaling pathway in tumor cells
The mammalian target of rapamycin kinase and tumor growth inhibtition
The ras signalling pathway as a target in cancer therapy
The mitogen-activated protein kinase pathway for molecular-targeted cancer treatment
Clinical relevance of tareted interference with Src-mediated signal transduction events.