rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Studies towards the total synthesis of the macrocyclic diamine alkaloid haliclonacyclamine C
  name:
    name part: Qu, Tao
    name part: 1978-
    role:
      role term: creator
  name:
    name part: Sulikowski, Gary A.
    role:
      role term: thesis advisor.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: txu
    date issued: 2005
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: remote
  abstract: Marine sponges produce a series of complex polycyclic diamine alkaloids which appear to have a common biogenesis from simple bis-pyridine macrocycles. These structurally novel secondary metabolites are presumably biosynthetically produced by the controlled ionic coupling of macrocyclic 3-alkyl piperidines leading to 3,4'-linked bis-piperidines (ii). Included among these diamine marine alkaloids is haliclonacyclamine C (i) which serves as our synthetic target. Chapter I in this thesis provides background information describing biological activity and proposed biosynthetic pathways to these important diamine marine alkaloids. Chapter II details progress towards the total synthesis of haliclonacyclamine C. The focus of Chapter II will be on our successful construction of the 3,4'-linked bispiperidine central core (ii) highlighted by the use of palladium-mediated C-C bond forming processes. The stereoselective hydrogenation of a coupled product will also be discussed.
  note: by Tao Qu.
  note: "Major Subject: Chemistry"
  note: Title from author supplied metadata (automated record created on Nov. , 09:45:50.)
  note: Vita.
  note: Abstract.
  note: Electronic resource.
  note: Mode of access: World Wide Web.
  note: System requirements: World Wide Web access and Adobe Acrobat Reader.
  note: M. S. Texas A&M University 2004.
  note: Includes bibliographical references.
  note: Text (Thesis).
  subject:
    topic: Major chemistry
  subject:
    topic: total synthesis
  subject:
    topic: marine alkaloids
  identifier: http://hdl.handle.net/1969.1/2738
  record info:
    record content source: TXA
    record creation date: 070104
    record change date: 20151104121356.0
    record identifier: in00002206453