rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Beta dose calculation in human arteries for various brachytherapy seed types
  name:
    name part: Yi, Sŭng-u.
    role:
      role term: creator
  name:
    name part: Reece, Warren Daniel
    role:
      role term: thesis advisor.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: txu
    date issued: 2004
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource.
  abstract: This dissertation explores beta dose profile of microspheres packed in arteries, various source geometries of ¹⁴²Pr that can be used for therapeutic purpose, and dose backscatter factors for selected beta sources. A novel treatment method by injecting microspheres into feeding arteries of arteriovenous malformation (AVM) is under pre-clinical investigation. To optimize radiation dose to the clinically important area, i.e. arterial wall, preliminary dosimetric studies were needed. Monte Carlo calculations were performed for several geometries simulating arteries filled with microspheres packed by random packing methods. Arterial radii used in the simulation varied from 50 [mu]m to 3 mm; microsphere radii varied from 10 [mu]m to 0.7 mm. Dose varied significantly as a function of microsphere size, for constant arterial sizes. For the same sizes of arteries, significant dose increase was observed because of inter-artery exposure for large arteries (> 0.1 cm rad.) filled with large microspheres (> 0.03 cm rad.). Dose increase between small arteries (0.03 cm rad.) was less significant. The dose profiles of prototype ¹⁴²Pr beta brachytherapy sources were calculated using MCNP 4C Monte Carlo code as well as dose point kernel (DPK) for selected cases. Dose profiles were similar to beta sources currently used indicating that ¹⁴²Pr can substitute for current sources for certain cases and the DPK was closely matched with MCNP result. Backscattering of electrons is a prominent secondary effect in beta dosimetry. The backscattering is closely correlated with factors such as geometry of source and scattering material, and composition of scattering material. The backscattering factors were calculated for selected beta sources that are currently used as well as potentially useful sources for therapeutic purpose. The factors were calculated as a function of distance from the interface between water and scatterers. These factors were fit by a simple function for future incorporation i…
  note: by Sung-Woo Lee.
  note: Vita.
  note: Abstract.
  note: "Major Subject: Nuclear Engineering"
  note: Title from author supplied metadata (record created on Jul. 18, 2005.)
  note: Electronic resource.
  note: System requirements: World Wide Web access and Adobe Acrobat Reader.
  note: Ph.D. Texas A&M University 2003.
  note: Includes bibliographical references.
  note: Text (Dissertation).
  subject:
    topic: Major nuclear engineering
  subject:
    topic: electron
  subject:
    topic: brachytherapy
  subject:
    topic: dose calculation
  subject:
    topic: beta
  subject:
    topic: Pr-142
  subject:
    topic: AVM
  identifier: http://hdl.handle.net/1969.1/42
  record info:
    record content source: TXA
    record creation date: 050728
    record change date: 20151102050844.0
    record identifier: in00002058550