Table of Contents:
  • The bacteria
  • Genome
  • What is a pneumococcus? / Christopher G. Dowson
  • Comparative genomics of s. pneumoniae : intra-strain diversity and genome plasticity / Hervé Tettelin and Susan Hollingshead
  • Surface anatomy
  • Capsule / Janet Yother
  • Choline-binding proteins / David Briles, Larry McDaniel and Edwin Swiatlo
  • Pneumolysin and other virulence proteins / Tim J. Mitchell
  • Microbial physiology
  • Cell wall hydrolases / Rubens Lopez ... [et al.]
  • Transformation / Sanford A. Lacks
  • Host-microbe interactions
  • Exposure and colonization
  • Evolutionary and population biology of streptococcus pneumoniae / Brian G. Spratt, William P. Hanage and Angela B. Brueggemann
  • Pneumococcal carriage / Derrick W. Crook ... [et al.]
  • Epidemiology of pneumococcal disease / Jay C. Butler
  • Mechanisms of carriage / Jeffrey N. Weiser
  • Invasion and infection
  • Inflammation and host defense / Paul Anthony Majcherczyk and Philippe Moreillon
  • Interactions of streptococcus pneumoniae with the proteins of the complement pathways / Margaret K. Hostetter
  • A pathogenetic categorization of clinical syndromes caused by streptococcus pneumoniae / Daniel M. Musher
  • Attachment and invasion of the respiratory tract / Elaine I. Tuomanen
  • Pathogenesis of pneumococcal meningitis / Joerg R. Weber
  • Immunodeficiency and invasive pneumococcal disease / Edward N. Janoff and Jeffrey B. Rubins
  • Treatment and prevention
  • Changing the ecology of pneumococci with antibiotics and vaccines / Ron Dagan and Marc Lipsitch
  • Pneumococcal infections : therapeutic strategies and pitfalls / Kathryn M. Edwards
  • Clinical relevance of antibiotic resistance in pneumococcal infections / Keith P. Klugman
  • Mechanisms for penicillin resistance in streptococcus pneumoniae : penicillin binding proteins, gene transfer, and cell wall metabolism / Carina Bergmann ... [et al.]
  • Macrolide, quinolone, and other non-β-lactam antibiotic resistance in streptococcus pneumoniae / Karita Ambrose and David S. Stephens
  • The humoral immune response to streptococcus pneumoniae / Clifford M. Snapper ... [et al.]
  • New pneumococcal vaccines : basic science developments / James C. Paton
  • Vaccine-induced immunity to Pneumonoccol infection / H. Käyhty and H. Mäkelä.