http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Developing a DNA vaccine to protect against brucellosis
viii, 22 leaves : illustrations ; 28 cm.
Brucella are Gram-negative intracellular pathogenic bacteria, which represent a threat to human and animal health. Live vaccine strains are available to protect some animal species but no vaccines exist for human use. A DNA vaccine could potentially provide long lasting cell-mediated protection against human brucellosis while minimizing the virulence risks associated with live vaccines. Five DNA vaccine candidates, each containing a different stress response gene from B. melitensis, have been constructed to test the theory that stress response genes delivered as a DNA vaccine could provide protection against Brucella infection. A reporter vaccine expressing green fluorescent protein has also been constructed to facilitate vaccine trafficking studies. It is not yet clear whether these vaccines can provide protection against brucellosis.
Fellows Thesis Texas A&M University 2003.
Includes bibliographical references (leaves 19-21).