rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Developing a DNA vaccine to protect against brucellosis
  name:
    name part: Owen, David Matthew.
    role:
      role term: creator
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: xx
    date issued: 2003
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    extent: viii, 22 leaves : illustrations ; 28 cm.
  abstract: Brucella are Gram-negative intracellular pathogenic bacteria, which represent a threat to human and animal health. Live vaccine strains are available to protect some animal species but no vaccines exist for human use. A DNA vaccine could potentially provide long lasting cell-mediated protection against human brucellosis while minimizing the virulence risks associated with live vaccines. Five DNA vaccine candidates, each containing a different stress response gene from B. melitensis, have been constructed to test the theory that stress response genes delivered as a DNA vaccine could provide protection against Brucella infection. A reporter vaccine expressing green fluorescent protein has also been constructed to facilitate vaccine trafficking studies. It is not yet clear whether these vaccines can provide protection against brucellosis.
  note: by David Matthew Owen.
  note: Vita.
  note: "Major Subject: Biochemistry".
  note: Group: Lifesciences.
  note: Fellows Thesis Texas A&M University 2003.
  note: Includes bibliographical references (leaves 19-21).
  subject:
    topic: Major biochemistry
  identifier: http://hdl.handle.net/1969.1/ETD-TAMU-2003-Fellows-Thesis-O94
  related item:
    location:
      url: http://hdl.handle.net/1969.1/ETD-TAMU-2003-Fellows-Thesis-O94
  record info:
    record content source: TXA
    record creation date: 030818
    record change date: 20151025090436.0
    record identifier: in00001778990