Effect of 1-[(E)-2-(2-methyl-4-nitrophenyl) diaz-1-enyl] pyrrolidine-2-carboxylic acid (LY29), a deaminase inhibitor, on ruminal protein metabolism in steers /
Two metabolic trials were conducted to assess the effects of the deaminase inhibitor 1-[(E)-2-(2-methyl-4-nitrophenyl) diaz-1-enyl] pyrrolidine-2-carboxylic acid (LY29), upon digestive parameters in Holstein steers. In trial one, steers with ruminal and duodenal cannulae were confined and fed a 16%...
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| Format: | Thesis Book |
| Language: | English |
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[Place of publication not identified] :
[publisher not identified] ;
2000.
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| Summary: | Two metabolic trials were conducted to assess the effects of the deaminase inhibitor 1-[(E)-2-(2-methyl-4-nitrophenyl) diaz-1-enyl] pyrrolidine-2-carboxylic acid (LY29), upon digestive parameters in Holstein steers. In trial one, steers with ruminal and duodenal cannulae were confined and fed a 16% crude protein, total mixed ration (trial 1). Experimental design consisted of five periods, each composed of two blocks of cannulated animals randomly assigned to different concentrations of LY29 (0, 800, and 1600 mg LY29₇head⁻¹₇d⁻¹). In trial two, the same cannulated steers were fed a 12% crude protein ryegrass hay diet in a two period crossover design examining two doses of LY29 (0 and 1600 mg LY29₇head⁻¹₇d⁻¹). Response variables analyzed included feed intake, average daily gain, ruminal ammonia, volatile fatty acids, duodenal digesta flux and concentrations of dry matter, organic matter, indigestible neutral detergent fiber, and total N. Results of trial one indicated that maximal response to LY29 was not achieved with 800 mg LY29₇head⁻¹₇d⁻¹. Therefore, mean responses to 1600 mgLY29₇head⁻¹₇d⁻¹ were used to evaluate induced changes in digestive parameters by LY29. Effects of LY29 were most pronounced in trial one resulting in significant (P<.05) responses in all measurements except total volatile fatty acids, average daily gains, and isovalerate concentrations. Duodenal flow of DM, OM, and N were depressed (P<.05) in trial one but enhanced (P<.05) in trial two in approximately the same proportions as LY29 affected feed DM intake. Also, average daily gain, and rumen ammonia concentrations were positive in trial two in contrast to being negative for trial one. Data presented demonstrated that type and extent of manipulation needed to maximize fermentative efficiency can be expected to vary with and depend upon the nature of the diet. |
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| Item Description: | Vita. "Major subject: Nutrition". In title, numerals are used. |
| Physical Description: | ix, 68 leaves ; 28 cm. Issued also on microfiche from Lange Micrographics. |
| Bibliography: | Includes bibliographical references (leaves 62-67). |