rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Cloning and characterization of the Aspergillus nidulans spdA gene
  name:
    name part: Jin, Yuan.
    role:
      role term: creator
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: xx
    date issued: 2000
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    form: remote
    extent: ix, 55 leaves : illustrations ; 28 cm.
  abstract: Using a PCR product amplified from Aspergillus nidulans DNA as a probe, the A. nidulans spdA gene, coding for a putative spermidine synthase, was isolated. Alignment of its deduced amino acid sequence with those of other spermidine synthases showed a high degree of identity. Northern blot analysis showed that the spdA mRNA accumulates at constant levels. This suggests that spermidine synthase transcript levels are not differentially regulated during development. To investigate the function of spermidine on differentiation and sterigmatocystin (ST) production of A. nidulans, we constructed a A. nidulans spdA null mutant by replacing a portion of the coding region with the argB gene. The spdA null mutant strain has an absolute requirement for spermidine for vegetative growth, sporulation, and ST production. Overexpression of flbA in the spdA null mutant strain activated conidiation and ST production. This result supports the hypothesis that polyamine effects on sporulation and ST production is mediated in part through the FlbA/FadA signaling pathway.
  note: by Yuan Jin.
  note: "Major subject: Plant Pathology".
  note: Vita.
  note: Also available online.
  note: Issued also on microfiche from Lange Micrographics.
  note: M.S. Texas A&M University 2000.
  note: Includes bibliographical references (leaves 48-54).
  subject:
    topic: Major plant pathology
  identifier: https://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-J57
  related item:
    location:
      url: https://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-J57
  record info:
    record content source: TXA
    record creation date: 010412
    record change date: 20220103134554.0
    record identifier: in00001606708