Quantitative Raman spectroscopy /
Raman spectroscopy has typically been used as a tool for the characterization of samples. As a quantitative method for predicting the concentration of sample components, the system developed in our labs required system characterization to understand the influence of different system parameters and t...
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| Format: | Thesis Book |
| Language: | English |
| Published: |
[Place of publication not identified] :
[publisher not identified] ;
1999.
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| Subjects: | |
| Online Access: | http://proxy.library.tamu.edu/login?url=http://proquest.umi.com/pqdweb?did=731685911&sid=1&Fmt=2&clientId=2945&RQT=309&VName=PQD |
| Summary: | Raman spectroscopy has typically been used as a tool for the characterization of samples. As a quantitative method for predicting the concentration of sample components, the system developed in our labs required system characterization to understand the influence of different system parameters and the development of robust statistical processing techniques for quantitative sample analysis. This work describes the characterization of the Raman spectroscopic probe and the statistical tools developed by the author. The tools include a method for removing spurious events in the detection system and an evolutionary approach to selecting the most appropriate detector channels to include in the statistical models used for prediction. The methods successfully increased model robustness, thereby improving the predictive capability of the chemometric model employed as demonstrated on several biomolecules. |
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| Item Description: | Vita. "Major Subject: Biomedical Engineering". |
| Physical Description: | ix, 81 leaves : illustrations ; 28 cm. Issued also on microfiche from University Microfilm Inc. |
| Bibliography: | Includes bibliographical references (leaves 66-71). |