Genetic manipulation of receptor expression and function /

Bibliographic Details
Other Authors: Accili, Domenico
Format: Book
Language:English
Published: New York : Wiley-Liss, [2000]
Series:Receptor biochemistry and methodology (Unnumbered)
Subjects:
Table of Contents:
  • Ch. 1. Transgenic rescue of mutant phenotypes using large DNA fragments
  • Ch. 2. Behavioral characterization of transgenic and knockout mice
  • Ch. 3. Genetic analysis of receptor phenotypes
  • Ch. 4. Immortalization of cell lines from transgenic and knockout mice by viral transformation
  • Ch. 5. The VP16-dependent binary system for inducible gene expression in transgenic mice
  • Ch. 6. Gene-targeting strategies in the analysis of alcohol and anesthetic mechanisms
  • Ch. 7. In vivo functions of the c-Met gene:(HGF/SF receptor)
  • Ch. 8. Tissue-specific knockouts of insulin receptor tyrosine kinase
  • Ch. 9. Targeted dominant negative mutations
  • Ch. 10. Toxin-mediated targeted cell ablation in vivo
  • Ch. 11. Antisense RNA-mediated inhibition of gene expression
  • Ch. 12. Delivery of antisense oligonucleotides to the brain to analyze receptor function.