Proline metabolism in enterocytes of neonatal pigs /

(1.0 mg/kg body weight), or vehicle solution (saline,

Bibliographic Details
Main Author: Dillon, Edgar Lichar
Format: Thesis eBook
Language:English
Published: [Place of publication not identified] : [publisher not identified] ; 1999.
Subjects:
Online Access:Link to OAKTrust copy
Description
Summary:(1.0 mg/kg body weight), or vehicle solution (saline,
0.0 - 10.0 my lactate. Amino acids were quantified by
1 ml) for 7 days. At l4-days of age, jugular venous
about the regulation of this metabolic pathway in
acids including proline. These results suggest the
ACTH had opposite embeds. ACTH decreased Vmax values
ACTH, may be beneficial in preventing the normal
adrenocorticotrophic hormone (ACTH) may be important
and in advancing intestinal maturation for successful
animals. On the basis of the previous studies with
arginine in suckling pigs compared with newborn pigs,
blood was withdrawn, and intestinal segments were
by lactate. As a result, lactate inhibited the
catabolism and whole body amino acid metabolism by
catabolism in piglets. To test this hypothesis, two
concentrations of histidine and other neutral amino
concentrations. Cortisol or ACTH increased treatment
cortical and ACTH in neonatal pigs. Cortisol, but not
decline in the intestinal synthesis of citrulline and
decreased in cortisol-treated piglets by 72%. Cortisol
differential regulation of intestinal proline
early weaning of piglets.
essential amino acid for neonates) but is rich in
examination. Cortisol and ACTH administration markedly
experimental series were conducted. In Experiment 1,
finding helps elucidate the mechanism responsible for
fold, respectively. Plasma ACTH concentrations
hepatic proline oxidate in rats, the author
high-performance liquid chromatography.
hydrocortisone 21-acetate (25 mg/kg body weight), ACTH
hyperladacidemia. In Experiment II, 7-day-old nursing
hypocitrullinemia and hypoargininemia in neonates with
hypothesized that lactate, codicil and
in the presence of 0.5 - 20 my proline and 0.0 - 15 my
increased in AcTH-treated piglets 3.l-fold but
increased plasma cortical concentrations 7.4- and 2.2-
intestinal synthesis of citrulline and arginine from
jejunal enterocytes were prepared from l4-day-old
Km values for proline, suggesting a decrease in enzyme
lactate. A double reciprocal plot of 1/IS) vs IN
lysine and ornithine, and ACTH also increased plasma
Mitochondria proline oxidate activity was determined
obtained for metabolic studies and histologists
of intestinal proline oxidate but had no effect on its
physiological regulators of intestinal proline
pigs received daily intramuscular injections of
pigs, and incubated at 370C in the
pigs, enterocytes play an important role in
plasma concentrations of branched-chain amino acids,
proline and glutamine plus glutamate. In neonatal
proline in a concentration-dependent manner. This
proline via proline oxidate. However, little is known
revealed noncompetitive inhibition of proline oxidizes
sequence of 2 my Iu-l4clproline, 2 AM glutamine 'and
Sow's milk is remarkably deficient in arginine (an raphics.
stimulated intestinal growth, proline transport, and
synthesis of citrulline and arginine from proline, but
synthesizing citrulline and arginine from dietary
Item Description:"Major subject: Nutrition".
Vita.
Physical Description:viii, 74 leaves : illustrations ; 28 cm.
Also available online.
Bibliography:Includes bibliographical references (leaves 63-69).