rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: TNF Alpha concentration in tumored and non-tumored Sinclair swine
  title info:
    title: TNF concentration in tumored and non-tumored Sinclair swine
  name:
    name part: Ash, Joan Olivia Rogers.
    role:
      role term: creator
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: xx
    date issued: 1998
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    form: remote
    extent: viii, 55 leaves : illustrations ; 28 cm.
  abstract: The infiltration of pigment-laden macrophages (PLM) in Sinclair swine cutaneous melanoma during the time frame in which histopathological evidence of tumor regression is observed suggests that they may play a role in this event. Tumor necrosis factor alpha (TNF[alpha]c) is a major cytotoxic secretagogue of activated macrophages. This study analyzed the circulating and intratumoral levels of TNF[alpha] in melanoma-positive and melanoma-free Sinclair swine over the first 100 days of age. TNF[alpha] concentrations were measured by porcine-specific TNF[alpha] ELISA. The mean serum TNF[alpha] concentration of all tumored pig samples combined (23.2 pg/n-d) was significantly higher than non-tumored pigs (15.97 pg/ml). However, comparisons of age groups between tumored and non-tumored pigs showed no significant differences. Comparisons of different ages within a tumor status group showed significant changes in serum TNF[alpha] concentrations. Intratumoral concentrations of TNF[alpha](X showed a significant decrease from 260.9 pg/ml to 40.4 pg/n-A over the first 100 days of age. These studies indicate that differences in TNF[alpha] serum and intratumoral concentrations occur in Sinclair swine and these may be correlated with age and tumor status.
  note: by Joan Olivia Rogers Ash.
  note: "Major subject: Veterinary Physiology".
  note: In title, symbols are used.
  note: Vita.
  note: Also available online.
  note: Issued also on microfiche from Lange Micrographics.
  note: M.S. Texas A&M University 1998.
  note: Includes bibliographical references: 42-52.
  subject:
    topic: Major veterinary physiology
  identifier: https://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-A84
  related item:
    location:
      url: https://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-A84
  record info:
    record content source: TXA
    record creation date: 990305
    record change date: 20220103134543.0
    record identifier: in00001465311