Impact Of Dorsolateral Periaqueductal Gray Lesions On Shock-Induced Hyperalgesia.
Prior exposure to shock lowers vocalization thresholds to heat and facilitates the acquisition of conditioned fear when training is conducted in a difference context. These observations have been taken as evidence that shock exposure increases the effective impact of subsequent aversive stimuli, a p...
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| Format: | Thesis Book |
| Language: | English |
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[College Station, Texas] :
Texas A&M University,
1998.
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| Online Access: | Link to OAK Trust copy Available on OAKTrust. |
| Summary: | Prior exposure to shock lowers vocalization thresholds to heat and facilitates the acquisition of conditioned fear when training is conducted in a difference context. These observations have been taken as evidence that shock exposure increases the effective impact of subsequent aversive stimuli, a phenomenon known as hyperalgesia. The present study explores whether this hyperalgesia depends on neurons within the dorsolateral periaqueductal gray (d1PAG). Experiment 1 showed that lesioning either the rostral or caudal diPAG prevented the shock-induced reduction in vocalization thresholds. Experiment 2 showed those lesioned subjects also failed to exhibit facilitated learning after shock exposure. Taken together, these results suggest that the diPAG play a critical role in the production of shock-induced hyperalgesia. |
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| Item Description: | "Major Subject: Psychology II". |
| Physical Description: | 1 online resource (27 pages). Digitized from print version held at Pickle Center High Density Storage, barcode 24829659 |
| Bibliography: | Includes bibliographical references: leaves 23-26. |