rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Non-invasive detection of protein kinase C Beta II and [], putative biomarkers for colon cancer using fecal messenger RNA
  name:
    name part: Aymond, Christin Marie.
    role:
      role term: creator
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: xx
    date issued: 1997
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    form: remote
    extent: x, 83 leaves : illustrations ; 28 cm.
  abstract: (p=0.025). We propose that expression of PKC [ ] and the
  abstract: (PKC) activity and isozyme expression, which may influence
  abstract: [ ]mMRNA expression, data were also expressed as a ratio
  abstract: a key role in the
  abstract: A sensitive technique for
  abstract: between PKC [ ]and [ ]. The ratio of PKC [ ]was
  abstract: carcinogen on PKC [ ],, and [ ] mRNA levels in feces was
  abstract: compared to animals without tumors, 0.50 ︢0.16
  abstract: detect potential markers for colon cancer. Weanling rats
  abstract: determined in order to develop non-invasive methodology to
  abstract: development of colon cancer. It has recently been shown that
  abstract: diagnosis can substantially
  abstract: dietary fat and fiber can alter colonic protein kinase C
  abstract: examined in this study. In addition, the effect of a
  abstract: factorial design. Fresh fecal samples (n=6 per treatment)
  abstract: Fecal PKC mRNA isozyme expression was altered by the
  abstract: having 2.5-fold lower PKC @ expression compared to saline
  abstract: higher in tumor bearing animals as compared to non-
  abstract: incidence exerts a reciprocal effect on fecal PKC [ ], and
  abstract: increased mucosal PKC [ ] MRNA expression compared with
  abstract: injected animals. Fecal PKC 01, mRNA expression was 3-fold
  abstract: injection of carcinogen (p < 0.03), with AOM injected animals
  abstract: mayserve as non-invasive markers for colon carcinogenesis.
  abstract: mucosal PKC [ ], expression was observed. Since tumor
  abstract: or azoxymethane (AOM; 15 mg/kg body weight) in a 2 x 2 x 2
  abstract: pectin and injected twice at one-week intervals with saline
  abstract: polymerase chain reaction (RT-PCR) performed using primers
  abstract: ratio of [ ]in feces
  abstract: reduce mortality.
  abstract: RNA was isolated and quantitative reverse transcriptase-
  abstract: saline controls. No main effect of tumor incidence on
  abstract: significantly higher in animals with tumors, 2.18 ︢1.25, as
  abstract: specific for the regulatory subunit of PKC [ ], and [ ].
  abstract: the expression of PKC [ ], and [ ]in fecal material was
  abstract: the malignant transformation process. The effect of diet on
  abstract: thedetection of colon cancer is of importance since early
  abstract: There is strong evidence that select dietary factors play
  abstract: tumor bearing animals (p < 0.03). In addition, AOM injection
  abstract: were collected 36 weeks after the second injection, poly A+
  abstract: were fed diets containing corn oil or fish oil, cellulose or
  note: by Christin Marie Aymond.
  note: "Major subject: Nutrition".
  note: In title, symbols are used.
  note: Vita.
  note: Also available online.
  note: Issued also on microfiche from Lange Micrographics.
  note: M.S. Texas A&M University 1997.
  note: Includes bibliographical references: pages 41-49.
  subject:
    topic: major nutrition
  identifier: https://hdl.handle.net/1969.1/ETD-TAMU-1997-THESIS-A96
  related item:
    location:
      url: https://hdl.handle.net/1969.1/ETD-TAMU-1997-THESIS-A96
  record info:
    record content source: TXA
    record creation date: 980923
    record change date: 20220103134706.0
    record identifier: in00001445897