Identification and characterization of the Anabaena sp. strain PCC 7120 hupL DNA rearrangement /

Arg3O8 and Tyr433 prevented XisC from rearranging the

Bibliographic Details
Main Author: Carrasco, Claudio D.
Format: Thesis eBook
Language:English
Published: [Place of publication not identified] : [publisher not identified] ; 1997.
Subjects:
Online Access:Link to OAKTrust copy
Description
Summary:Arg3O8 and Tyr433 prevented XisC from rearranging the
artificial substrate in E. coli.
at least three programmed DNA rearrangements occur during
bp direct repeats that flank the element. The predicted HupL
differentiated cells specialized for nitrogen fixation.
differentiation and involve the deletion of DNA elements from
differentiation are uncommon and have been described in only
during the late stages of heterocyst development. The
element. Inactivation of xisc in the chromosome of Anabaena
encodes the recombinase required for excision of the hupl
Expression of xisc in E. coli is sufficient to cause site-
heterocyst differentiation. Heterocysts are terminally
HupTLTV operon and is thought to be involved in regulation of
hydrogenase and to HupU. An open reading frame, named xisc,
nitrogen fixation genes; hupl message was detected only
PCC 7120 prevents rearrangement of the hupl element.
polypeptide is homologous to the large subunit of [NiFe]
predicted product of a gene located upstream of hupl, shows
predicted XisC protein shows sequence similarity to XisA, the
Programmed DNA rearrangements that occur during cellular
rearrangement a 10.5-kb DNA element is excised from within
recombinase required for excision of the nifd element, and to
recombinases. Site-directed mutagenesis of the invariant
sequence similarity to the small subunit of uptake
specific rearrangement of an artificial substrate. The
the catalytic domain of the Int family of site-specific
the hupl gene by site-specific recombination between two 16-
These rearrangements take place late during heterocyst
two prokaryotic organisms. In Anabaena sp. strain PCC 7120
uptake hydrogenase. hupl is expressed similarly to the
uptake hydrogenases and to HupU which forms part of the
was identified near one end of the hupl DNA element and
within the nifd, fdxn, and hupl genes. In the hupl
Item Description:"Major subject: Microbiology".
In title, numerals and symbols are used.
Vita.
Physical Description:viii, 79 leaves : illustrations ; 28 cm.
Also available online.
Issued also on microfiche from Lange Micrographics.
Bibliography:Includes bibliographical references.