Synthetic peptide combinatorial libraries : an approach to identifying antimicrobials for the control of plant pathogens /
(66-10)(FRLKFH) and a fully-defined pentapeptide
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| Format: | Thesis eBook |
| Language: | English |
| Published: |
[Place of publication not identified] :
[publisher not identified] ;
1996.
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| Subjects: | |
| Online Access: | Link to OAKTrust copy |
| Summary: | (66-10)(FRLKFH) and a fully-defined pentapeptide (AG- 1). Initial screening of the 400 peptide mixture (PPD1)(FRLHF) were developed from the iterative steps. The 10 and PPD1. The peptides did not demonstrate mutagenic or 30 []/mi PPD1 as compared to the uninjected control trees. ability of PPD1 to control oak wilt, in vivo, caused by C. activity against the selected fungi. Hexapeptide, 66-10, and against the above mentioned fungi , as well as, Ceratocystis antimicrobials to control the growth of phytopathogenic carcinogenic properties. Studies of the mode of action of comparable to selected commercial fungicides. Mutagenicity consisting of 400 different peptide mixtures was synthesized. defined peptides were compared to commercial antifungals for fagacearum and Pythium ultimum. A fully-defined hexapeptide fagacearum, was determined. A significant reduction in first two amino acid residues were designated. Additional fungi. A synthetic peptide combinatorial hexapeptide library Fusarium oxysporum f.sp. lycopersici and Rhizoctonia solani libraries involved in the iterative steps were screened library identified biologically active peptide mixtures whose pentapeptide, PPD1, exhibited activity that was somewhat Peptides are not only key regulators of physiological percent crown loss was observed for trees injected with PPD1 against C. fagacearum, the test isolate, suggested that processes, but also have the potential of acting as testing using the Ames Salmonella plate incorporation assay, The library was tested for biological activity against the potential target of PPD1 may be the cell membrane. The with and without metabolic activation, was performed with 66- |
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| Item Description: | "Major subject: Plant Pathology". Vita. |
| Physical Description: | xi, 117 leaves : illustrations ; 28 cm. Also available online. Issued also on microfiche from Lange Micrographics. |
| Bibliography: | Includes bibliographical references: pages 111-115. |