Acceleration of wound healing in young and aged rats /
(ACM), a complex plant carbohydrate and macrophage
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| Format: | Thesis eBook |
| Language: | English |
| Published: |
[Place of publication not identified] :
[publisher not identified] ;
1996.
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| Subjects: | |
| Online Access: | Link to OAKTrust copy |
| Summary: | (ACM), a complex plant carbohydrate and macrophage ACM-stimulated killed macrophages were significantly activity. Additionally, we observed changes in the cytokine MRNA aged rats. Studies were conducted using both ACM injection, agent, and encourages further studies into the basis of its and macrophage supplementation to the wound site. Acemannan and old animals was significantly (cc<0.05) reduced. ACM animals was significantly (u.<O.05) reduced. There was no average CWA exposed over the course of healing in both young between the CWA seen in old control versus young control closure decreased and average Cumulative Wound Area (CWA) closure. This thesis focuses on the ability of Acemannan days to heal in a 2 year old rat. It is our belief that this decreased wound closure and CWA over that seen in the control defect present in senescence, and that macrophage activation different (cc<0.05) from all other treatments, and exhibited exposed over the course of healing in both young and old healing in young and old rats. Again, there was no healing in young and old rats. Overall time to complete impairment in healing may be due in part to a macrophage injection to the wound site was found to accelerate wound macrophages stimulated with ACM. The acceleration seen in macrophages to the wound site was found to accelerate wound or supplementation may yield an acceleration in wound peritoneal macrophages to accelerate wound healing. However, production for TGF-P, TNF-ot, and IL-6 in young and old significant difference between the young and old treated significant difference between young and old ACM-treated stimulation did not significantly improve the ability of stimulator, to accelerate wound healing in both young and these studies strengthens the case of ACM as a wound healing Wound healing in the aged is delayed. A 6 mm punch biopsy wound heals in 13 days in a 3 month old rat, but takes 21 wounds, but there was a significant (CC<0.05) difference wounds. Killed, untreated macrophages were not effective. wounds. Likewise, a single injection of peritoneal wounds. Overall time to complete closure decreased and |
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| Item Description: | "Major subject: Veterinary Microbiology". Vita. |
| Physical Description: | x, 54 leaves : illustrations ; 28 cm. Also available online. Issued also on microfiche from Lange Micrographics. |
| Bibliography: | Includes bibliographical references: pages 45-53. |