The effect of acemannan immunostimulant on a wound healing model /

accelerates wound healing by examining wound fluid and

Bibliographic Details
Main Author: Kennon, Katherine Ann, 1962-
Format: Thesis eBook
Language:English
Published: [Place of publication not identified] : [publisher not identified] ; 1996.
Subjects:
Online Access:Link to OAKTrust copy
Description
Summary:accelerates wound healing by examining wound fluid and
Acemannan is a complex carbohydrate composed primarily of
acetylated mannans and galacturonic acid. It is prepared by
activity, cell proliferative effects, protein composition and
barrier between new granulation tissue and preexistent
binding proteins. Wound chamber tissue was analyzed both
chamber granulation tissue. Tissue from treated chambers
characteristics. Acemannan treated wound fluid contained a
contained more collagen; as meaned by both biochemical and
control. Wound fluid was extracted every other day for
cytoplasmic spreading in endothelial cells. These studies
designed to investigate the manner by which acemannan
different between acemannan and control. Acemannan treated
endothelial cells. Acemannan treated wound fluid induced
fourteen days and at the end of the treatment period the
gel. Acemannan has several important therapeutic properties
granulation tissue. The wire mesh wound chamber allows for
histologically and chemically for collagen content. Total
implanted subcutaneously in the lateral dorsal area then
including acceleration of wound healing, reduction of
inflammation, immunomodulation, and antitumor effects. The
injected with either 2 mg/ml acemannan or saline as a
lower percentage of macrophages than the control. The most
morphological analyses. Studies were conducted to determine
neutrophils and neutrophils having degenerative morphological
process by which acemannan induces these therapeutic
properties is not completely understood. This study was
protein and nitric oxide levels were not significantly
repair cells, and modulation of inflammatory cells.
sequential analysis of the wound fluid, provides a physical
sequential ethanol precipitation of the A loe vera L. leaf
significant difference was observed in collagen content of
significantly greater fibroblast proliferation and
suggest that acemannan accelerates the rate of wound healing
the effects of exposure to wound fluid on fibroblasts and
through increased collagen deposition, stimulation of tissue
through the healing process. Wound chambers were surgically
tissue, and the contents of the chamber proceed naturally
wound chambers were removed and the tissue was extracted.
wound fluid contained a higher percentage of total
Wound fluid was analyzed for nitric oxide, metalloproteinase
Item Description:"Major subject: Veterinary Microbiology".
Vita.
Physical Description:xii, 147 leaves : illustrations ; 28 cm.
Also available online.
Issued also on microfiche from Lange Micrographics.
Bibliography:Includes bibliographical references.