Protein structure /

Bibliographic Details
Main Author: Darby, N. J.
Other Authors: Creighton, Thomas E., 1940-
Format: Book
Language:English
Published: Oxford ; New York : IRL Press at Oxford University Press, [1993]
Series:In focus (Oxford, England)
Subjects:
Table of Contents:
  • Basic aspects of polypeptide structure
  • Covalent structures of proteins
  • Non-covalent forces in protein structure
  • Electrostatic interactions
  • van der Waals interactions
  • Hydrogen bonds
  • Hydrophobic interactions
  • Amino acid residues
  • Primary structures of proteins
  • Three-dimensional aspects of polypeptide structure
  • Conformations of polypeptides
  • Regular polypeptide structures
  • Structures of fibrous proteins
  • Silk fibroin
  • Collagen
  • Coiled-coils
  • Three-dimensional structures of proteins
  • Determining protein structure
  • CD spectroscopy
  • X-ray diffraction
  • NMR spectroscopy
  • Structural organization in globular proteins
  • Tertiary structure
  • Protein interiors and exteriors
  • Secondary structure
  • Loops and turns
  • Disulphide bonds
  • Domains
  • Supersecondary structure and folding patterns
  • Quaternary structure
  • Flexibility in protein structures
  • Evolutionarily related proteins
  • Predicting protein structure
  • Protein design
  • Proteins in solution and in membranes
  • Proteins in aqueous solution
  • Aqueous solubility
  • Ionization.
  • (cont) Membrane proteins
  • Stability of the folded state
  • Unfolding
  • Thermodynamics of unfolding
  • Rationalizing protein stability
  • Other factors that affect protein stability
  • Protein folding
  • General characteristics of protein folding
  • Identifying folding intermediates
  • Biosynthetic folding
  • Ligand binding and protein function
  • Ligand binding
  • Studying protein-ligand interactions
  • General properties of protein-ligand interactions
  • Relationship between protein structure and ligand binding
  • Calcium-binding proteins
  • Redox proteins
  • Nucleotide-binding proteins
  • DNA-binding proteins
  • Helix-turn-helix proteins
  • Zinc-containing DNA recognition elements
  • Other DNA-binding motifs
  • Regulation of ligand binding
  • Allosteric regulation
  • Reversible covalent modification.