http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Mechanical loading attenuates loss of bone mass and bone strength induced by immobilization and calcium-deficiency
0.01% calcium. The IL group had the same treatment as the
and calcium-deficient diet ( I group) decreased cortical BNM
and ultimate load (r=0.754) and BMD and stiffness (r=0.793).
and ultimate load by three-point bending to failure, cross-
ANOVA. When results were found to be significant, Student
BMD was only 2.37o lower than the control group mean, and
by 12%, ultimate load by 19@o and stiffness by 19.77o, when
cause a decrease in strength and bone mineral loss, and
chow containing 1.85% calcium. The I group had one hindlimb
compared to control rats.2. External loading at 34N, 36
cycles @ 2 Hz, three times per week attenuates the decrease
density (BMD) by dual energy X-ray absorptiometry, stiffness
exercise is known to strengthen bone. The purpose of this
Immobilization and calcium-deficiency have been documented to
immobilized (I) group or an immobilized-loaded (IL) group.
immobilized by taping and fed a low calcium diet containing
immobilized group but had the immobilized limb mechanically
in BMD and ultimate load in this model. The IL group mean
loaded by a unique four-point loading machine three times per
modulus of elasticity. All comparisons were done by one-way
Newman-Keuls Method post hoc tests when performed. Final
parameters of bone mass and bone strength in bone subjected
results indicate: 1. Six weeks of immobilization by taping
sacrificed, both tibia removed and tested for bone mineral
sectional moment of inertia, cross-sectional area, and
study was to determine the effects of mechanical loading on
The C group had no immobilization and were fed a regular rat
This indicates BNM is an effective predictor of bone
this model significant correlations were found between BMD
to immobilization and calcium-deficiency. Adult female rats
ultimate load was 107o lower than the control group. 3. In
week. After six weeks of treatment, all animals were
were randomly assigned to either a control group (C),
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