Mechanistic and structural studies of nitroalkane oxidase from Fusarium oxysporum /

a ping pong mechanism. The pH dependence of the V/K data are

Bibliographic Details
Main Author: Heasley, Carl J.
Format: Thesis eBook
Language:English
Published: [Place of publication not identified] : [publisher not identified] ; 1995.
Subjects:
Online Access:Link to OAKTrust copy
Description
Summary:a ping pong mechanism. The pH dependence of the V/K data are
aidehyde or ketone. The enzyme was purified by using a three
carbon position. The enzyme activity is dependent on added
consistent with the enzyme having an ionizable group which
denitrification of a nitroalkane to the corresponding
mechanistic studies of nitroalkane oxidase from Fusarium
must be deprotonated for activity with a pKa of 6.8 and a
N-terminus has been determined.
nitroethane, 1 -nitropropane, and 1 -nitropentane, all fit to
oxidized flavin. In addition, the amino acid sequence of the
oxysponim. Nitroalkane oxidase catalyzes the oxidative
perform many analyses. The substrates used to date,
requirement for the substrate to be protonated in the a
step purification scheme in large enough quantities to
This thesis describes the purification and the initial
Item Description:"Major subject: Biochemistry".
Vita.
Physical Description:x, 31 leaves : illustrations ; 28 cm.
Also available online.
Issued also on microfiche from Lange Micrographics.
Bibliography:Includes bibliographical references.