Enrofloxacin and amikacin pharmacokinetics in Scimitar-horned oryx (Oryx dammah) following a single intravenous dose /
(1.OAg/ml) which is bactericidal against most sensitive
| Main Author: | |
|---|---|
| Format: | Thesis eBook |
| Language: | English |
| Published: |
[Place of publication not identified] :
[publisher not identified] ;
1995.
|
| Subjects: | |
| Online Access: | Link to OAKTrust copy |
| Summary: | (1.OAg/ml) which is bactericidal against most sensitive 0.152+0.02L/kg, clearance, 1.2+0.4ml/min/kg, and MRT, 1.3mg/kg for enrofloxacin, derived from metabolic energy 1.887+0.632btg/ml and mean elimination half -life of 136.5+49.Omin. Mean serum amikacin concentrations reached 173.63+147.5Ag/min/ml, volume of distribution, 0.80+0.30L/kg, 41.2+27.5min. Model-independent parameters for amikacin were adult Scimitar-horned oryx (Oryx dammah) were determined. amikacin concentrations were above selected bacterial MIC for appeared to have underestimated the oryx drug requirements. AUC, 5478+2828Ag/min/ml, volume of distribution, bacteria (0.5iAg/ml) consistently for 90min. The minimum bacteria and remained above the MIC of other sensitive clearance, 12.07+7.12ml/min/kg, and MRT, 77.22+72.8min. Mean concentrations against susceptible bacteria. The dose curve was best fit to a two-compartment model with maximum enrofloxacin dose would be administered parenterally to For enrofloxacin, model-independent parameters were AUC, loxacin, the curve was best fit to one-compartment model with maximum serum concentration after distribution of mean elimination half -life of 97.0+31.8min. For enrof recommended peak concentrations (25[]g/ml) and below the recommended trough concentration (2[]g/ml) by 8hr. The serum scaling. For amikacin, the drug concentration versus time Scimitar-horned oryx at 1.6mg/kg every 6-8hr for serum Scimitar-horned oryx at 12hr intervals should produce serum concentration after distribution of 30.5+4.7[]g/ml and serum enrofloxacin concentrations reached the recommended MIC Single dose pharmacokinetics of amikacin and enrofloxacin in The (mean) intravenous doses were 5.8mg/kg for amikacin and therapeutic serum concentrations for susceptible bacteria. up to 6hr. This amikacin dose administered parenterally to |
|---|---|
| Item Description: | "Major subject: Veterinary Physiology". Vita. |
| Physical Description: | X, 88 leaves : illustrations ; 28 cm. Also available online. Issued also on microfiche from Lange Micrographics. |
| Bibliography: | Includes bibliographical references. |