Glycosyl tetrazoles as glycosyl donors for the synthesis of 2-deoxy glycosides /
2-Deoxy oligosaccharides form a major component of
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| Format: | Thesis eBook |
| Language: | English |
| Published: |
[Place of publication not identified] :
[publisher not identified] ;
1995.
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| Subjects: | |
| Online Access: | Link to OAKTrust copy |
| Summary: | 2-Deoxy oligosaccharides form a major component of antibiotics. The instability of 2-deoxy oligosaccharides and assembly of a trisaccharide model system of PI-080. biologically active aureolic acid and angucycline butylphosphoramidite produces N2 and N1 isomer of the Condensation of 2-deoxy sugars with 1H-tetrazole and di-t- conditions. Repetition of the coupling protocol enables the difficulty in controlling their stereoselectivity of coupling glycosyl donors were examined under different glycosylation in the synthesis of oligosaccharides. reactions is primarily due to the lack of a C-2 substituent. Synthesis of this trisaccharide demonstrates the synthetic tetrazole adduct. Glycosylations using either isomers as This thesis introduces a new method of 2-deoxy glycosylation. utility of glycosyl tetrazoles as potential glycosyl donors |
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| Item Description: | "Major subject: Chemistry". In title, numerals are used. Vita. |
| Physical Description: | xiii, 107 leaves : illustrations ; 28 cm. Also available online. Issued also on microfiche from Lange Micrographics. |
| Bibliography: | Includes bibliographical references. |