Deterministic effects of discrete radioactive particles on skin /
The deterministic effects of discrete radioactive particles
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| Format: | Thesis Book |
| Language: | English |
| Published: |
[Place of publication not identified] :
[publisher not identified] ;
1994.
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| Subjects: | |
| Online Access: | http://proxy.library.tamu.edu/login?url=http://proquest.umi.com/pqdweb?did=741965771&sid=1&Fmt=2&clientId=2945&RQT=309&VName=PQD |
| Summary: | The deterministic effects of discrete radioactive particles on the skin of Hanford Miniature Swine were studied using a mixture of sources of various sizes and beta energies. Exposures were made with the sources in contact with the skin and elevated slightly off-skin. The sources included activation sources of 6OCo and 170Tm, and fissioned U02 microspheres. The dose needed to produce an effect at a 50% rate of occurrence (ED50) was determined for each source type. The ED50 dose for ulceration for the '170Tm disk sources of I mm and 5 mm diameter were 20 ︢5 and 21 ︢5 Gy, respectively. The ED50 for ulceration with the 300 [ ]m and 1 mm U02 microspheres was 27 ︢10 and 35 ︢10 Gy, respectively. The ED50 ulceration dose for the 1 mm 60CO source was 35+ 8Gy. Reporting the dose as a 1cm2 average depth of 70 [ ] in the skin was shown to be the most effective method for predicting deterministic effects. The ED50 values demonstrated virtually no energy dependence for the different source types and were also independent of the source size when a 1 cm2 area dose was used. Additionally, the ED50 values for the off-skin exposures were the same as contact exposures based on 1 cm2 doses. |
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| Item Description: | Vita. "Major Subject: Nuclear Engineering". |
| Physical Description: | xvii, 244 leaves : illustrations ; 28 cm. Issued also on microfiche from University Microfilms Inc. |
| Bibliography: | Includes bibliographical references. |