Cryopreservation of equine oocytes using glycerol as the cryoprotectant and cumulus investment as a parameter /

A study was conducted to determine the viability of equine

Bibliographic Details
Main Author: Lippert, Jennifer Johnson, 1968-
Format: Thesis eBook
Language:English
Published: [Place of publication not identified] : [publisher not identified] ; 1995.
Subjects:
Online Access:Link to OAKTrust copy
Description
Summary:A study was conducted to determine the viability of equine
abattoir and transported to the lab in physiologic saline
and 3) corona radiata only. All oocytes were stained with
bound organelles such as endoplasmic reticulum and Golgi,
categories based on cumulus investment. These categories
cryopreserved equine oocytes could not be determined.
establishing they were nonviable. The oocytes were then
expansion as a second check of viability. None of the
fluorescein diacetate (FDA) to determine viability before
freezing. Forty viable oocytes from each group were frozen
frozen equine oocytes as compared to fresh equine oocytes
loss of microvilli on oocyte, disruption of single membrane
maturation media. The oocytes were then stained with orcein
membrane. The protocol evaluated in this study was not
metaphase 11 after 36 h in the maturation media, further
methods in this experiment.
migration of intact organelles away from the periphery of the
needle. Recovered oocytes were assigned to one of three
of the 120 oocytes showed fluorescent activity, thus
One viable oocyte from each group was frozen to be evaluated
oocyte and lack of cortical granule alignment at oocyte cell
oocytes cryopreserved in glycerol and to determine whether
oocytes exhibited cumulus expansion after exposure to the
placed in maturation media and evaluated visually for cumulus
postthaw by transmission electron microscopy. The most
significant ultrastructural differences observed in the
solution. Follicles were aspirated using a syringe and
stage of cumulus investment at freezing had an effect on
successful in maintaining viability of equine oocytes
their survival. Ovaries were collected from mares at an
Therefore, the effect of cumulus morphology on viability of
throughout the freeze-thaw process as evaluated by the
to be evaluated post-thaw using FDA and orcein stains. None
to determine metaphase state. None of the oocytes were in
verifying that none of the oocytes were viable post-thaw.
were disrupted plasma membranes of cumulus cells and oocyte,
were: 1) complete cumulus layer; 2) partial cumulus layer;
Item Description:"Major subject: Physiology of Reproduction".
Vita.
Physical Description:xi, 65 leaves : illustrations ; 28 cm.
Also available online.
Issued also on microfiche from Lange Micrographics.
Bibliography:Includes bibliographical references.