Evaluation of fat sources on cholesterol and lipoproteins using genetically selected pigs as human models /
At approximately 8 weeks of age, four-way cross (Chester
| Main Author: | |
|---|---|
| Format: | Thesis Book |
| Language: | English |
| Published: |
[Place of publication not identified] :
[publisher not identified] ;
1994.
|
| Subjects: | |
| Online Access: | http://proxy.library.tamu.edu/login?url=http://proquest.umi.com/pqdweb?did=741965281&sid=1&Fmt=2&clientId=2945&RQT=309&VName=PQD |
| Summary: | At approximately 8 weeks of age, four-way cross (Chester White x Landrace x Large White x Yorkshire) pigs (n = 24) were selected based on genetically high (H) or low (L) serum cholesterol levels - 12 from each genetic group - to determine the relationship between genetics, fat source and sex class on serum cholesterol, growth, carcass characteristics, and the cholesterol and lipid content of muscle and adipose tissues. Boars and gilts, six each from the two genetic groups, were assigned randomly to one of three dietary treatments for 46 days. A standard grower diet was modified to include either beef tallow (T), corn oil (CR) or coconut oil (CC), and the pigs were given ad libitum access to feed. Cholesterol was added to each diet to ensure that the measured changes were due to fat sources and not cholesterol differences between the diets. There were no differences between boars and gilts at the initial evaluation or at the end of the treatment; therefore, means were pooled for statistical analyses. No differences were found for live weights taken on day 1, 18, 29 and 46. The CR diet had a higher apparent digestibility (P <.01) than the T or CC diets, but genetic background did not influence apparent digestibility. Blood samples were taken on day 1, 29, and 46 via the jugular vein. The total serum cholesterol concentration was different between the two genetic groups at the start of the study (H = 1296︢, L = 1045︢; P <.Ol). The ending values (H = 1511︢0, L = 1307︢) were not significantly different; however, the same trend occurred. Differences (P < .01) were found between dietary treatments for total cholesterol on day 29 (T = 1781︢1, CR = 1291︢0, CC = 1518︢), but by day 46, differences were resolved. Pigs were slaughtered on day 46, and carcass data were collected. There were no differences in fat deposition at the first rib, 10th rib, last rib, or last lumbar vertebra, but differences were found between genetic groups for longissimus muscle area (H = 21.0.︢8, L = 18.11︢.0; P <.05) and USDA muscle score (H = 2.1.︢l, L = 1.7.︢l; P <.05). There were no differences in cholesterol content of the pre-rigor or post-rigor longissimus muscle for either genetics or diet. Neither genetics nor dietary treatment affected the cholesterol content of the adipose tissue. However, the pre-rigor muscle tissue also had lower values for the cholesterol content than did the post-rigor tissues. There were no differences in fat percentage between genetic groups for any of the tissues analyzed. However, there was a genetic group X sex class interaction for the post-rigor longissimus fat content. There were differences in total lipid content among the dietary treatments for the pre-rigor and post-rigor longissimus muscle. Overall, genetic background had an impact on serum cholesterol, and dietary fat intake influenced lipid content in muscle tissues. |
|---|---|
| Item Description: | Vita. "Major Subject: Nutrition". |
| Physical Description: | xi, 47 leaves : illustrations ; 28 cm. Issued also on microfiche from University Microfilms Inc. |
| Bibliography: | Includes bibliographical references. |